KIAA0753 and GCC1

Data Source:
BioGRID (two hybrid)

		KIAA0753	GCC1
Description		KIAA0753	GRIP and coiled-coil domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Centriolar Satellite	Golgi Trans Cisterna Golgi Membrane Golgi Apparatus Cytosol
	Molecular Function	Protein Binding	Protein Binding Small GTPase Binding
	Biological Process	Centriole Replication Protein Localization To Centrosome
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Familial lung cancer ( 29924316) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Pulse pressure ( 28135244 27841878 30578418) Systolic blood pressure ( 27841878 30578418)	Feeling worry ( 29500382) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Medication adherence in chronic diseases ( 25317111) Refractive error ( 32231278) Type 2 diabetes ( 26818947 22158537 30718926)
Interacting Genes		20 interacting genes: AARD BHLHA9 BRPF1 C1orf109 CCHCR1 CT55 FAM161A GCC1 HGS KIFC3 MNS1 RNF6 ROPN1 SMARCD1 SUOX TCHP TEAD4 USHBP1 ZNF114 ZNF777	64 interacting genes: ABI2 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC33 CCDC85B CEP57 CEP70 COIL CPSF7 DISC1 DNAJA3 FAM83A FBF1 FBXO28 FIGNL1 FOSL1 GAS8 GLI1 GOLGA2 GTF2I HDX ICA1L IKBKG ITSN1 KATNAL1 KDM1A KIAA0753 KIAA1217 KIF5B LCA5 LZTS2 MCRS1 MED4 MEOX1 MID2 NAB2 NAV1 NECAB2 NINL OIP5 PAK5 PPP1R18 PPP1R27 PRPF18 RUNX1 SMARCD1 SPOP TFIP11 TLE5 TP53BP2 TRIM29 TRIM50 USHBP1 UTP14C XIAP ZC4H2 ZFP90 ZNF276
Entrez ID		9851	79571
HPRD ID		11106	07599
Ensembl ID		ENSG00000198920	ENSG00000179562
Uniprot IDs		Q2KHM9	A4D0Z4 Q96CN9
PDB IDs
Enriched GO Terms of Interacting Partners?
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