KIAA0753 and BRPF1

Data Source:
BioGRID (two hybrid)

		KIAA0753	BRPF1
Description		KIAA0753	bromodomain and PHD finger containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Centriolar Satellite	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Plasma Membrane MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Binding	DNA Binding Protein Binding Acetyltransferase Activator Activity Histone Binding Histone Acetyltransferase Activity (H3-K23 Specific) Metal Ion Binding
	Biological Process	Centriole Replication Protein Localization To Centrosome	Histone H3 Acetylation Histone H3-K23 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity Regulation Of Signal Transduction By P53 Class Mediator
Pathways			HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Familial lung cancer ( 29924316) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Pulse pressure ( 28135244 27841878 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		20 interacting genes: AARD BHLHA9 BRPF1 C1orf109 CCHCR1 CT55 FAM161A GCC1 HGS KIFC3 MNS1 RNF6 ROPN1 SMARCD1 SUOX TCHP TEAD4 USHBP1 ZNF114 ZNF777	11 interacting genes: CDCA7L CEP63 CEP70 GTF2H1 H3C14 ING5 KIAA0753 NECAB1 PBXIP1 USHBP1 USP20
Entrez ID		9851	7862
HPRD ID		11106	03875
Ensembl ID		ENSG00000198920	ENSG00000156983
Uniprot IDs		Q2KHM9	P55201
PDB IDs			2D9E 2RS9 2X35 2X4W 2X4X 2X4Y 3L42 3MO8 4LC2 4QYD 4QYL 4UYE 5C6S 5C7N 5C85 5C87 5C89 5D7X 5DY7 5DYA 5DYC 5E3D 5E3G 5EM3 5EPR 5EPS 5EQ1 5ERC 5ETB 5ETD 5EV9 5EVA 5EWC 5EWD 5EWH 5EWV 5EWW 5FFV 5FFW 5FFY 5FG4 5FG5 5G4R 5G4S 5MWG 5MWH 5MWZ 5MYG 5O4S 5O4T 5O55 5O5A 5O5F 5O5H 5OV8 5OWA 5OWB 5OWE 5T4U 5T4V 6EKQ 6U04 7C4I
Enriched GO Terms of Interacting Partners?
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