Wiki-Pi
About
Search
Browse
People
Updates
Search
BRPF1 and CEP70
Data Source:
BioGRID
(two hybrid)
BRPF1
CEP70
Description
bromodomain and PHD finger containing 1
centrosomal protein 70
Image
No pdb structure
GO Annotations
Cellular Component
Histone Acetyltransferase Complex
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Cytosol
Plasma Membrane
MOZ/MORF Histone Acetyltransferase Complex
Centrosome
Cytosol
Molecular Function
DNA Binding
Protein Binding
Acetyltransferase Activator Activity
Histone Binding
Histone Acetyltransferase Activity (H3-K23 Specific)
Metal Ion Binding
Protein Binding
Identical Protein Binding
Gamma-tubulin Binding
Biological Process
Histone H3 Acetylation
Histone H3-K23 Acetylation
Histone H3-K14 Acetylation
Positive Regulation Of Transcription, DNA-templated
Regulation Of Catalytic Activity
Regulation Of Signal Transduction By P53 Class Mediator
G2/M Transition Of Mitotic Cell Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Microtubule Cytoskeleton Organization
Ciliary Basal Body-plasma Membrane Docking
Pathways
HATs acetylate histones
Regulation of TP53 Activity through Acetylation
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease (
29631575
)
Male-pattern baldness (
28196072
)
Interacting Genes
11 interacting genes:
CDCA7L
CEP63
CEP70
GTF2H1
H3C14
ING5
KIAA0753
NECAB1
PBXIP1
USHBP1
USP20
242 interacting genes:
ABT1
AGBL2
AKAP17A
ARHGEF3
ARMCX1
ATP5PO
ATXN7
BARD1
BAZ2B
BEX2
BRD1
BRMS1
BRMS1L
BRPF1
BYSL
C1orf35
C7orf25
C8orf33
CARD9
CAVIN3
CBX8
CCDC187
CCDC85B
CDC37
CDC73
CDCA7L
CEP57L1
CFAP53
CLPB
COIL
CWF19L2
DAXX
DAZAP2
DDX41
DDX6
DNAJB11
DNTTIP2
DVL3
EAF1
EBNA1BP2
EIF3D
ELOA
ELOA2
EMD
EMP1
ENKD1
ERCC3
FAM118B
FAM124A
FAM133A
FAM13C
FAM161A
FAM161B
FAM214B
FAM90A1
GADD45GIP1
GAS8
GATAD2B
GCC1
GEM
GLYCTK
GPATCH2L
GPATCH4
GPX7
GSE1
HAUS1
HDAC4
HDAC6
HIC2
HMGB4
HOXB5
HOXC8
HSPD1
IK
INO80B
INPP5J
IPCEF1
IQCE
IQUB
ITPKB
KANK2
KANSL1
KAT14
KAT5
KAT7
KDM1A
KRI1
KRT31
LAMTOR5
LCOR
LENG1
LENG8
LIN37
LNX1
MAB21L2
MAGOH
MBD3
MCM10
MCRS1
MEST
METTL17
MFAP1
MKRN3
MRPL44
NEBL
NIPSNAP3A
NKAP
NKAPD1
NOL12
NOP2
NOP53
NOXA1
NRIP1
NTAQ1
NUSAP1
ODAD4
PAM16
PIBF1
PIMREG
PKN1
PLA2G2A
PPFIA1
PPIG
PPP1R16B
PPP1R18
PRKRIP1
PRPF18
PRPF3
PRPF31
PSMA1
PSORS1C2
RASSF10
RBM10
RCOR3
RHPN1
RNF169
RNF6
RPL13
SCNM1
SEC14L1
SERPINH1
SETD5
SFR1
SH2D4A
SLU7
SMARCE1
SNRPD2
SNW1
SOD2
SPANXN3
SRGN
SSX3
STK25
STMN2
SUV39H1
SUV39H2
SYT17
SYTL4
SYTL5
TAF1D
TBC1D22B
TBC1D30
TCAF1
TCEANC
TEAD4
TLK2
TRAF3IP3
TRIM29
TRIM3
TRIM42
TSFM
TSGA10IP
TSHZ3
TTLL10
TXLNB
TXN2
USP2
UTP11
UTP14A
UTP14C
UTP25
UTP3
VXN
WT1
YJU2
ZBTB16
ZBTB24
ZBTB4
ZBTB47
ZBTB48
ZBTB49
ZBTB8A
ZCCHC10
ZFC3H1
ZFHX3
ZFP1
ZFP91
ZGPAT
ZNF136
ZNF140
ZNF148
ZNF165
ZNF169
ZNF17
ZNF20
ZNF202
ZNF227
ZNF239
ZNF264
ZNF266
ZNF302
ZNF329
ZNF35
ZNF366
ZNF408
ZNF410
ZNF417
ZNF426
ZNF433
ZNF439
ZNF490
ZNF491
ZNF555
ZNF557
ZNF572
ZNF574
ZNF578
ZNF587
ZNF599
ZNF607
ZNF648
ZNF669
ZNF688
ZNF696
ZNF775
ZNF777
ZNF785
ZNF835
ZNF860
ZSCAN12
ZSCAN21
ZSCAN23
Entrez ID
7862
80321
HPRD ID
03875
16779
Ensembl ID
ENSG00000156983
ENSG00000114107
Uniprot IDs
P55201
A0A140VJG2
B7Z2D2
Q8NHQ1
PDB IDs
2D9E
2RS9
2X35
2X4W
2X4X
2X4Y
3L42
3MO8
4LC2
4QYD
4QYL
4UYE
5C6S
5C7N
5C85
5C87
5C89
5D7X
5DY7
5DYA
5DYC
5E3D
5E3G
5EM3
5EPR
5EPS
5EQ1
5ERC
5ETB
5ETD
5EV9
5EVA
5EWC
5EWD
5EWH
5EWV
5EWW
5FFV
5FFW
5FFY
5FG4
5FG5
5G4R
5G4S
5MWG
5MWH
5MWZ
5MYG
5O4S
5O4T
5O55
5O5A
5O5F
5O5H
5OV8
5OWA
5OWB
5OWE
5T4U
5T4V
6EKQ
6U04
7C4I
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?