Wiki-Pi
About
Search
Browse
People
Updates
Search
RAB11A and PSEN2
Data Source:
HPRD
(two hybrid, in vivo)
RAB11A
PSEN2
Description
RAB11A, member RAS oncogene family
presenilin 2
Image
No pdb structure
GO Annotations
Cellular Component
Spindle Pole
Endosome
Multivesicular Body
Golgi Apparatus
Trans-Golgi Network
Centrosome
Kinetochore Microtubule
Cytosol
Transport Vesicle
Axon
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Vesicle
Cleavage Furrow
Protein-containing Complex
Centriolar Satellite
Intracellular Membrane-bounded Organelle
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Recycling Endosome
Recycling Endosome Membrane
Extracellular Exosome
Schaffer Collateral - CA1 Synapse
Postsynaptic Recycling Endosome
Glutamatergic Synapse
Golgi Membrane
Kinetochore
Nucleus
Nuclear Inner Membrane
Mitochondrial Inner Membrane
Lysosomal Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Centrosome
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Cortex
Cell Surface
Membrane
Apical Plasma Membrane
Z Disc
Growth Cone
Neuromuscular Junction
Protein-containing Complex
Ciliary Rootlet
Neuronal Cell Body
Dendritic Shaft
Membrane Raft
Perinuclear Region Of Cytoplasm
Gamma-secretase Complex
Molecular Function
GTPase Activity
Protein Binding
GTP Binding
Microtubule Binding
Syntaxin Binding
Myosin V Binding
Endopeptidase Activity
Protein Binding
Aspartic Endopeptidase Activity, Intramembrane Cleaving
Biological Process
Renal Water Homeostasis
Exocytosis
Mitotic Metaphase Plate Congression
Positive Regulation Of Epithelial Cell Migration
Regulation Of Multivesicular Body Size
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Vesicle-mediated Transport
Astral Microtubule Organization
Neuron Projection Development
Melanosome Transport
Regulation Of Cytokinesis
Protein Localization To Cell Surface
Multivesicular Body Assembly
Post-translational Protein Modification
Positive Regulation Of Axon Extension
Regulation Of Long-term Neuronal Synaptic Plasticity
Plasma Membrane To Endosome Transport
Regulation Of Protein Transport
Establishment Of Vesicle Localization
Regulation Of Vesicle-mediated Transport
Establishment Of Protein Localization To Organelle
Protein Localization To Plasma Membrane
Establishment Of Protein Localization To Membrane
Mitotic Spindle Assembly
Ciliary Basal Body-plasma Membrane Docking
Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane
Vesicle-mediated Transport In Synapse
Amyloid-beta Clearance By Transcytosis
Positive Regulation Of Protein Localization To Plasma Membrane
Exosomal Secretion
Membrane Protein Ectodomain Proteolysis
Calcium Ion Transport
Notch Receptor Processing
Protein Processing
Membrane Protein Intracellular Domain Proteolysis
Amyloid-beta Formation
Notch Receptor Processing, Ligand-dependent
Intracellular Signal Transduction
Amyloid Precursor Protein Catabolic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of Catalytic Activity
Ephrin Receptor Signaling Pathway
Amyloid-beta Metabolic Process
Regulation Of Calcium Import Into The Mitochondrion
Mitochondrion-endoplasmic Reticulum Membrane Tethering
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Vasopressin regulates renal water homeostasis via Aquaporins
Anchoring of the basal body to the plasma membrane
VxPx cargo-targeting to cilium
TBC/RABGAPs
RAB geranylgeranylation
Nuclear signaling by ERBB4
Regulated proteolysis of p75NTR
NRIF signals cell death from the nucleus
Activated NOTCH1 Transmits Signal to the Nucleus
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
NOTCH2 Activation and Transmission of Signal to the Nucleus
EPH-ephrin mediated repulsion of cells
NOTCH3 Activation and Transmission of Signal to the Nucleus
NOTCH4 Activation and Transmission of Signal to the Nucleus
Noncanonical activation of NOTCH3
Drugs
5'-Guanosine-Diphosphate-Monothiophosphate
Guanosine-5'-Diphosphate
Diseases
Alzheimer's disease (AD)
GWAS
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Mean corpuscular hemoglobin (
29403010
32888494
27863252
)
Mean corpuscular hemoglobin concentration (
29403010
)
Mean corpuscular volume (
29403010
32888494
27863252
)
Mean spheric corpuscular volume (
32888494
)
Neutrophil count (
32888494
)
Neutrophil percentage of white cells (
32888494
)
Red blood cell count (
27863252
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Heel bone mineral density (
30598549
)
Refractive error (
32231278
)
Interacting Genes
32 interacting genes:
ARF5
ARF6
CHMP1B
CHMP3
DTNBP1
GDI2
IKBKG
KAT2B
MYO5A
MYO5B
OPTN
PPP2R1A
PPP2R1B
PSEN1
PSEN2
PTGIR
RAB11FIP1
RAB11FIP2
RAB11FIP3
RAB11FIP4
RAB11FIP5
RAB13
RAB3IL1
RAB3IP
RAB8A
RABGGTB
RCHY1
SEC13
STX4
TBXA2R
TDP2
WDR44
61 interacting genes:
AAMP
ACTG1
AP1G1
APH1A
APH1B
APP
AURKA
BCL2L1
CAPN1
CASP1
CASP3
CASP6
CASP7
CASP8
CEP55
CFLAR
CHKA
CIB1
CSNK1A1
CSNK1D
CSNK2A1
CTNNB1
CTNND2
DNAJB1
DOCK3
ECD
EID1
ELAVL1
EVI5L
EXOC6
FBXL12
FHL2
FLNA
FLNB
GCDH
GFAP
HLA-DMB
HPS1
ICAM5
IFIT3
IFIT5
KCNIP3
KCNIP4
LIPF
MAST1
METTL2B
NCSTN
NOS3
NOTCH1
NOTCH2
NOTCH3
NOTCH4
OGA
PDCD4
PSENEN
RAB11A
RHEB
RNF32
SPC24
SRI
UBQLN1
Entrez ID
8766
5664
HPRD ID
05715
02860
Ensembl ID
ENSG00000103769
ENSG00000143801
Uniprot IDs
A0A024R5Z8
P62491
P49810
PDB IDs
1OIV
1OIW
1OIX
1YZK
2D7C
2GZD
2GZH
2HV8
4C4P
4D0L
4D0M
4LWZ
4LX0
4UJ3
4UJ4
4UJ5
5C46
5C4G
5EUQ
5EZ5
5FBL
5FBQ
5FBR
5FBV
5FBW
5JCZ
6DJL
6IXV
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?