Description |
presenilin 2 |
notch receptor 4 |
Image |
No pdb structure |
No pdb structure |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Advanced glycation end-product levels ( 26083729)
- Age-related macular degeneration ( 22694956)
- Aspartate aminotransferase levels ( 29403010)
- Asthma ( 21804548 31619474)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Bipolar disorder ( 31043756)
- Blood protein levels ( 28240269)
- Blood protein levels in cardiovascular risk ( 28369058)
- Chronic hepatitis B infection ( 25802187)
- Circulating myeloperoxidase levels (serum) ( 23620142)
- Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947)
- Colorectal cancer ( 30529582)
- Crohn's disease ( 23266558)
- Epstein-Barr virus immune response (EBNA-1) ( 23326239)
- Food antigen IgG levels ( 24962563)
- Hematocrit ( 32888494)
- Hemoglobin ( 32888494)
- High light scatter reticulocyte count ( 32888494)
- HIV-1 control ( 20041166)
- Inflammatory bowel disease ( 28067908)
- Iron status biomarkers (iron levels) ( 28334935)
- Joint mobility (Beighton score) ( 27182965)
- Longevity ( 30294719)
- Lung cancer ( 28604730)
- Lung cancer in ever smokers ( 28604730)
- Lupus nephritis in systemic lupus erythematosus ( 24925725)
- Migraine ( 27322543)
- Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection ( 25030430)
- Obesity-related traits ( 23251661)
- Objective response to lithium treatment in bipolar disorder ( 26503763)
- Prostate cancer ( 23535732)
- Reticulocyte count ( 32888494)
- Reticulocyte fraction of red cells ( 27863252)
- Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
- Schizophrenia ( 19571808 30285260 23894747)
- Squamous cell lung carcinoma ( 28604730)
- Systemic lupus erythematosus ( 21408207)
- Systemic sclerosis ( 21779181)
- Takayasu arteritis ( 25604533)
- Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
- Ulcerative colitis ( 24837172 28067908)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for body mass index ( 28448500)
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Interacting Genes |
61 interacting genes:
AAMP
ACTG1
AP1G1
APH1A
APH1B
APP
AURKA
BCL2L1
CAPN1
CASP1
CASP3
CASP6
CASP7
CASP8
CEP55
CFLAR
CHKA
CIB1
CSNK1A1
CSNK1D
CSNK2A1
CTNNB1
CTNND2
DNAJB1
DOCK3
ECD
EID1
ELAVL1
EVI5L
EXOC6
FBXL12
FHL2
FLNA
FLNB
GCDH
GFAP
HLA-DMB
HPS1
ICAM5
IFIT3
IFIT5
KCNIP3
KCNIP4
LIPF
MAST1
METTL2B
NCSTN
NOS3
NOTCH1
NOTCH2
NOTCH3
NOTCH4
OGA
PDCD4
PSENEN
RAB11A
RHEB
RNF32
SPC24
SRI
UBQLN1
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13 interacting genes:
DLL4
EGFL7
ELOC
FBXW7
MAML1
MAML2
MAML3
PSEN1
PSEN2
RBPJ
SMAD2
SMAD3
SMAD4
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Entrez ID |
5664 |
4855 |
HPRD ID |
02860 |
01290 |
Ensembl ID |
ENSG00000143801
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ENSG00000204301
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Uniprot IDs |
P49810
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A0A1U9X983
Q99466
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PDB IDs |
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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