BECN1 and SGF29

Data Source:
BioGRID (two hybrid)

		BECN1	SGF29
Description		beclin 1	SAGA complex associated factor 29
Image
GO Annotations	Cellular Component	Phagophore Assembly Site Nucleus Mitochondrion Endosome Autophagosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Trans-Golgi Network Cytosol Endosome Membrane Extrinsic Component Of Membrane Dendrite Mitochondrial Membrane Phosphatidylinositol 3-kinase Complex, Class III, Type I Phosphatidylinositol 3-kinase Complex, Class III, Type II Phosphatidylinositol 3-kinase Complex, Class III Phagocytic Vesicle	SAGA Complex Ada2/Gcn5/Ada3 Transcription Activator Complex SAGA-type Complex
	Molecular Function	Protein Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Phosphatidylinositol 3-kinase Binding GTPase Binding	Protein Binding Enzyme Binding Methylated Histone Binding Protein N-terminus Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Response To Hypoxia Autophagy Apoptotic Process Cellular Defense Response Cellular Response To Nitrogen Starvation Lysosome Organization Mitotic Metaphase Plate Congression Aging Negative Regulation Of Cell Population Proliferation Response To Iron(II) Ion Response To Lead Ion Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Viral Process Macroautophagy Protein Deubiquitination Regulation Of Cytokinesis Receptor Catabolic Process Response To Vitamin E Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Response To Drug Negative Regulation Of Apoptotic Process Engulfment Of Apoptotic Cell Early Endosome To Late Endosome Transport Late Endosome To Vacuole Transport Neuron Development Amyloid-beta Metabolic Process Regulation Of Catalytic Activity Cell Division Defense Response To Virus Negative Regulation Of Cell Death Cellular Response To Hydrogen Peroxide Cellular Response To Aluminum Ion Cellular Response To Copper Ion Cellular Response To Epidermal Growth Factor Stimulus Response To Mitochondrial Depolarisation Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Negative Regulation Of Autophagosome Assembly Negative Regulation Of Lysosome Organization Negative Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Autophagosome Assembly Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Histone Acetylation Histone H3 Acetylation Establishment Of Protein Localization To Chromatin
Pathways		Macroautophagy Ub-specific processing proteases Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	HATs acetylate histones
Drugs		Estradiol Estradiol acetate Estradiol benzoate Estradiol cypionate Estradiol dienanthate Estradiol valerate
Diseases
GWAS		Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		59 interacting genes: AKT1 AMBRA1 ARAF ARNT ATG3 BCL2 BCL2L1 BCL2L10 BTK CASP3 CCND2 CDK4 CDK6 CDKN2A CDKN2B EPHA2 ERBB2 FGFR4 FRS2 FZR1 GFI1B GLIS2 GOPC GRM1 HERC5 ITCH ITPR1 ITPR3 KAT2A KDELR2 LATS2 MAP2K3 MAP2K5 MAP2K6 MAPKAPK2 MAPKAPK3 MDM4 MST1 NF2 NXF1 PDGFRA PGK1 RACK1 RAF1 SENP3 SGF29 SHD SMAD2 STK11 STYK1 TEAD2 TERT TRAF2 TSC1 UBC ULK1 WASHC1 XPO1 YES1	30 interacting genes: BECN1 C20orf202 CCDC102B CCDC158 CLHC1 DBF4B H3-4 KNSTRN KRT13 KRT15 KRT16 KRT19 KRT24 KRT27 KRT33B LNX1 LZTS1 MED11 MED4 MYF5 NDC80 PROSER3 RINT1 SYCE3 SYNPO TADA3 TCF4 TEX12 TFIP11 TRAF3IP1
Entrez ID		8678	112869
HPRD ID		05087	13996
Ensembl ID		ENSG00000126581	ENSG00000176476
Uniprot IDs		A0A024R1X5 B4DQ36 E7EV84 Q14457 W0FFG4	Q96ES7
PDB IDs		2P1L 2PON 3DVU 4DDP 4MI8 5EFM 5HHE 5VAU 5VAX 5VAY 6DCN 6DCO 6HOI 6HOJ 6HOK	3LX7 3ME9 3MEA 3MET 3MEU 3MEV 3MEW 5C0M
Enriched GO Terms of Interacting Partners?
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