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BECN1 and TEAD2
Data Source:
BioGRID
(fluorescent resonance energy transfer)
BECN1
TEAD2
Description
beclin 1
TEA domain transcription factor 2
Image
GO Annotations
Cellular Component
Phagophore Assembly Site
Nucleus
Mitochondrion
Endosome
Autophagosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Trans-Golgi Network
Cytosol
Endosome Membrane
Extrinsic Component Of Membrane
Dendrite
Mitochondrial Membrane
Phosphatidylinositol 3-kinase Complex, Class III, Type I
Phosphatidylinositol 3-kinase Complex, Class III, Type II
Phosphatidylinositol 3-kinase Complex, Class III
Phagocytic Vesicle
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytosol
Intracellular Membrane-bounded Organelle
TEAD-YAP Complex
Molecular Function
Protein Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Phosphatidylinositol 3-kinase Binding
GTPase Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Coactivator Binding
DNA-binding Transcription Factor Activity
Protein Binding
Disordered Domain Specific Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Autophagosome Assembly
Autophagy Of Mitochondrion
Mitophagy
Response To Hypoxia
Autophagy
Apoptotic Process
Cellular Defense Response
Cellular Response To Nitrogen Starvation
Lysosome Organization
Mitotic Metaphase Plate Congression
Aging
Negative Regulation Of Cell Population Proliferation
Response To Iron(II) Ion
Response To Lead Ion
Positive Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Viral Process
Macroautophagy
Protein Deubiquitination
Regulation Of Cytokinesis
Receptor Catabolic Process
Response To Vitamin E
Cellular Response To Amino Acid Starvation
Cellular Response To Glucose Starvation
Response To Drug
Negative Regulation Of Apoptotic Process
Engulfment Of Apoptotic Cell
Early Endosome To Late Endosome Transport
Late Endosome To Vacuole Transport
Neuron Development
Amyloid-beta Metabolic Process
Regulation Of Catalytic Activity
Cell Division
Defense Response To Virus
Negative Regulation Of Cell Death
Cellular Response To Hydrogen Peroxide
Cellular Response To Aluminum Ion
Cellular Response To Copper Ion
Cellular Response To Epidermal Growth Factor Stimulus
Response To Mitochondrial Depolarisation
Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Negative Regulation Of Autophagosome Assembly
Negative Regulation Of Lysosome Organization
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Positive Regulation Of Autophagosome Assembly
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Vasculogenesis
Neural Tube Closure
Embryonic Heart Tube Morphogenesis
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Notochord Development
Hippo Signaling
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Paraxial Mesoderm Development
Lateral Mesoderm Development
Embryonic Organ Development
Negative Regulation Of Cell Death
Protein-containing Complex Assembly
Cellular Response To Retinoic Acid
Regulation Of Stem Cell Differentiation
Pathways
Macroautophagy
Ub-specific processing proteases
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
YAP1- and WWTR1 (TAZ)-stimulated gene expression
RUNX3 regulates YAP1-mediated transcription
Drugs
Estradiol
Estradiol acetate
Estradiol benzoate
Estradiol cypionate
Estradiol dienanthate
Estradiol valerate
Diseases
GWAS
Type 2 diabetes (age of onset) (
28060188
)
Interacting Genes
59 interacting genes:
AKT1
AMBRA1
ARAF
ARNT
ATG3
BCL2
BCL2L1
BCL2L10
BTK
CASP3
CCND2
CDK4
CDK6
CDKN2A
CDKN2B
EPHA2
ERBB2
FGFR4
FRS2
FZR1
GFI1B
GLIS2
GOPC
GRM1
HERC5
ITCH
ITPR1
ITPR3
KAT2A
KDELR2
LATS2
MAP2K3
MAP2K5
MAP2K6
MAPKAPK2
MAPKAPK3
MDM4
MST1
NF2
NXF1
PDGFRA
PGK1
RACK1
RAF1
SENP3
SGF29
SHD
SMAD2
STK11
STYK1
TEAD2
TERT
TRAF2
TSC1
UBC
ULK1
WASHC1
XPO1
YES1
45 interacting genes:
AKT1
ARNT
AURKA
BCL2L15
BECN1
C14orf39
CCND2
CDK4
CDK6
CDKN2A
CDKN2B
DACH1
EPHA2
FGFR4
FZR1
GLIS1
GLIS2
GNG13
HGF
HIF1A
INPP5A
LATS2
MAP2K3
MAP2K5
MAP3K5
MYC
NCOA1
NEDD4
NFIC
NSD3
RAF1
RASSF1
RUNX1
SAA2
SOX3
STK11
TERT
TP53
TRIM3
USF2
VGLL1
VGLL3
VGLL4
WWTR1
YAP1
Entrez ID
8678
8463
HPRD ID
05087
03432
Ensembl ID
ENSG00000126581
ENSG00000074219
Uniprot IDs
A0A024R1X5
B4DQ36
E7EV84
Q14457
W0FFG4
A0A024QZE2
Q15562
PDB IDs
2P1L
2PON
3DVU
4DDP
4MI8
5EFM
5HHE
5VAU
5VAX
5VAY
6DCN
6DCO
6HOI
6HOJ
6HOK
3L15
5DQ8
5DQE
5EMV
5HGU
6CDY
6E5G
6S60
6S64
6S66
6S69
6S6J
6UYB
6UYC
6VAH
Enriched GO Terms of Interacting Partners
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