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SGF29 and BECN1
Data Source:
BioGRID
(two hybrid)
SGF29
BECN1
Description
SAGA complex associated factor 29
beclin 1
Image
GO Annotations
Cellular Component
SAGA Complex
Ada2/Gcn5/Ada3 Transcription Activator Complex
SAGA-type Complex
Phagophore Assembly Site
Nucleus
Mitochondrion
Endosome
Autophagosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Trans-Golgi Network
Cytosol
Endosome Membrane
Extrinsic Component Of Membrane
Dendrite
Mitochondrial Membrane
Phosphatidylinositol 3-kinase Complex, Class III, Type I
Phosphatidylinositol 3-kinase Complex, Class III, Type II
Phosphatidylinositol 3-kinase Complex, Class III
Phagocytic Vesicle
Molecular Function
Protein Binding
Enzyme Binding
Methylated Histone Binding
Protein N-terminus Binding
Protein Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Phosphatidylinositol 3-kinase Binding
GTPase Binding
Biological Process
Histone Acetylation
Histone H3 Acetylation
Establishment Of Protein Localization To Chromatin
Autophagosome Assembly
Autophagy Of Mitochondrion
Mitophagy
Response To Hypoxia
Autophagy
Apoptotic Process
Cellular Defense Response
Cellular Response To Nitrogen Starvation
Lysosome Organization
Mitotic Metaphase Plate Congression
Aging
Negative Regulation Of Cell Population Proliferation
Response To Iron(II) Ion
Response To Lead Ion
Positive Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Viral Process
Macroautophagy
Protein Deubiquitination
Regulation Of Cytokinesis
Receptor Catabolic Process
Response To Vitamin E
Cellular Response To Amino Acid Starvation
Cellular Response To Glucose Starvation
Response To Drug
Negative Regulation Of Apoptotic Process
Engulfment Of Apoptotic Cell
Early Endosome To Late Endosome Transport
Late Endosome To Vacuole Transport
Neuron Development
Amyloid-beta Metabolic Process
Regulation Of Catalytic Activity
Cell Division
Defense Response To Virus
Negative Regulation Of Cell Death
Cellular Response To Hydrogen Peroxide
Cellular Response To Aluminum Ion
Cellular Response To Copper Ion
Cellular Response To Epidermal Growth Factor Stimulus
Response To Mitochondrial Depolarisation
Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Negative Regulation Of Autophagosome Assembly
Negative Regulation Of Lysosome Organization
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Positive Regulation Of Autophagosome Assembly
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
HATs acetylate histones
Macroautophagy
Ub-specific processing proteases
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Estradiol
Estradiol acetate
Estradiol benzoate
Estradiol cypionate
Estradiol dienanthate
Estradiol valerate
Diseases
GWAS
Type 2 diabetes (age of onset) (
28060188
)
Interacting Genes
30 interacting genes:
BECN1
C20orf202
CCDC102B
CCDC158
CLHC1
DBF4B
H3-4
KNSTRN
KRT13
KRT15
KRT16
KRT19
KRT24
KRT27
KRT33B
LNX1
LZTS1
MED11
MED4
MYF5
NDC80
PROSER3
RINT1
SYCE3
SYNPO
TADA3
TCF4
TEX12
TFIP11
TRAF3IP1
59 interacting genes:
AKT1
AMBRA1
ARAF
ARNT
ATG3
BCL2
BCL2L1
BCL2L10
BTK
CASP3
CCND2
CDK4
CDK6
CDKN2A
CDKN2B
EPHA2
ERBB2
FGFR4
FRS2
FZR1
GFI1B
GLIS2
GOPC
GRM1
HERC5
ITCH
ITPR1
ITPR3
KAT2A
KDELR2
LATS2
MAP2K3
MAP2K5
MAP2K6
MAPKAPK2
MAPKAPK3
MDM4
MST1
NF2
NXF1
PDGFRA
PGK1
RACK1
RAF1
SENP3
SGF29
SHD
SMAD2
STK11
STYK1
TEAD2
TERT
TRAF2
TSC1
UBC
ULK1
WASHC1
XPO1
YES1
Entrez ID
112869
8678
HPRD ID
13996
05087
Ensembl ID
ENSG00000176476
ENSG00000126581
Uniprot IDs
Q96ES7
A0A024R1X5
B4DQ36
E7EV84
Q14457
W0FFG4
PDB IDs
3LX7
3ME9
3MEA
3MET
3MEU
3MEV
3MEW
5C0M
2P1L
2PON
3DVU
4DDP
4MI8
5EFM
5HHE
5VAU
5VAX
5VAY
6DCN
6DCO
6HOI
6HOJ
6HOK
Enriched GO Terms of Interacting Partners
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