SGF29 and KRT16

Data Source:
BioGRID (two hybrid)

		SGF29	KRT16
Description		SAGA complex associated factor 29	keratin 16
Image			No pdb structure
GO Annotations	Cellular Component	SAGA Complex Ada2/Gcn5/Ada3 Transcription Activator Complex SAGA-type Complex	Nucleus Cytosol Cytoskeleton Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding Enzyme Binding Methylated Histone Binding Protein N-terminus Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Histone Acetylation Histone H3 Acetylation Establishment Of Protein Localization To Chromatin	Morphogenesis Of An Epithelium Inflammatory Response Cytoskeleton Organization Aging Keratinocyte Differentiation Negative Regulation Of Cell Migration Keratinization Hair Cycle Innate Immune Response Intermediate Filament Cytoskeleton Organization Keratinocyte Migration Establishment Of Skin Barrier Cornification
Pathways		HATs acetylate histones	Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Non-epidermolytic palmoplantar keratoderma (NEPPK) Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS
Interacting Genes		30 interacting genes: BECN1 C20orf202 CCDC102B CCDC158 CLHC1 DBF4B H3-4 KNSTRN KRT13 KRT15 KRT16 KRT19 KRT24 KRT27 KRT33B LNX1 LZTS1 MED11 MED4 MYF5 NDC80 PROSER3 RINT1 SYCE3 SYNPO TADA3 TCF4 TEX12 TFIP11 TRAF3IP1	56 interacting genes: AMOT ARFIP2 C1orf109 C1orf216 CARD9 CCDC146 CCDC17 CCHCR1 CCNC CDK18 CYTH4 EPM2AIP1 GAS8 GNG10 HGS KIFC3 KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LMO1 LNX1 MBD3 PKN1 POLL PPP1R18 PRKAA2 PRPH PUS10 SEMA4C SGF29 SMARCD1 SMARCE1 SNAPIN TCHP TSG101 TTC23 TXLNB USHBP1
Entrez ID		112869	3868
HPRD ID		13996	01018
Ensembl ID		ENSG00000176476	ENSG00000186832
Uniprot IDs		Q96ES7	P08779
PDB IDs		3LX7 3ME9 3MEA 3MET 3MEU 3MEV 3MEW 5C0M
Enriched GO Terms of Interacting Partners?
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