TLR10 and FUT7

Data Source:
HPRD (two hybrid)

		TLR10	FUT7
Description		toll like receptor 10	fucosyltransferase 7
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane	Golgi Apparatus Trans-Golgi Network Membrane Integral Component Of Membrane Golgi Cisterna Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Activity Identical Protein Binding NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating	Protein Binding Fucosyltransferase Activity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase Activity Alpha-(1->3)-fucosyltransferase Activity
	Biological Process	Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Inflammatory Response Immune Response Toll-like Receptor 10 Signaling Pathway Innate Immune Response Positive Regulation Of Inflammatory Response	Regulation Of Type IV Hypersensitivity CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Leukocyte Migration Involved In Immune Response Leukocyte Migration Involved In Inflammatory Response Protein Glycosylation Ceramide Metabolic Process Inflammatory Response Embryo Implantation Regulation Of Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Fucosylation L-fucose Catabolic Process Positive Regulation Of Cell Adhesion Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cell Adhesion Molecule Production Lymphocyte Migration Into Lymphoid Organs Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Neutrophil Extravasation
Pathways		Toll Like Receptor 10 (TLR10) Cascade IRAK4 deficiency (TLR5) MyD88 cascade initiated on plasma membrane	Lewis blood group biosynthesis
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29785011) Allergic rhinitis ( 30013184) Allergic sensitization ( 23817571) Asthma ( 31361310 31959851 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Diabetes in response to antihypertensive drug treatment (treatment strategy interaction) ( 27670767) Endometriosis or endometrial cancer (pleiotropy) ( 29608257) Helicobacter pylori serologic status ( 23652523) Limited cutaneous systemic scleroderma ( 29293537) Self-reported allergy ( 23817569) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537)	Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494)
Interacting Genes		12 interacting genes: CAT ECH1 F8A1 FLNA FUT7 GLDC LUC7L3 MYD88 PTPN6 TLR1 TLR2 TRIM54	3 interacting genes: CTXN3 CXCL9 TLR10
Entrez ID		81793	2529
HPRD ID		05884	03611
Ensembl ID		ENSG00000174123	ENSG00000180549
Uniprot IDs		A0A024R9W4 Q9BXR5	Q11130
PDB IDs		2J67
Enriched GO Terms of Interacting Partners?
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