FUT7 and TLR10

Data Source:
HPRD (two hybrid)

		FUT7	TLR10
Description		fucosyltransferase 7	toll like receptor 10
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Membrane Integral Component Of Membrane Golgi Cisterna Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Protein Binding Fucosyltransferase Activity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase Activity Alpha-(1->3)-fucosyltransferase Activity	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Activity Identical Protein Binding NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating
	Biological Process	Regulation Of Type IV Hypersensitivity CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Leukocyte Migration Involved In Immune Response Leukocyte Migration Involved In Inflammatory Response Protein Glycosylation Ceramide Metabolic Process Inflammatory Response Embryo Implantation Regulation Of Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Fucosylation L-fucose Catabolic Process Positive Regulation Of Cell Adhesion Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cell Adhesion Molecule Production Lymphocyte Migration Into Lymphoid Organs Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Neutrophil Extravasation	Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Inflammatory Response Immune Response Toll-like Receptor 10 Signaling Pathway Innate Immune Response Positive Regulation Of Inflammatory Response
Pathways		Lewis blood group biosynthesis	Toll Like Receptor 10 (TLR10) Cascade IRAK4 deficiency (TLR5) MyD88 cascade initiated on plasma membrane
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29785011) Allergic rhinitis ( 30013184) Allergic sensitization ( 23817571) Asthma ( 31361310 31959851 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Diabetes in response to antihypertensive drug treatment (treatment strategy interaction) ( 27670767) Endometriosis or endometrial cancer (pleiotropy) ( 29608257) Helicobacter pylori serologic status ( 23652523) Limited cutaneous systemic scleroderma ( 29293537) Self-reported allergy ( 23817569) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537)
Interacting Genes		3 interacting genes: CTXN3 CXCL9 TLR10	12 interacting genes: CAT ECH1 F8A1 FLNA FUT7 GLDC LUC7L3 MYD88 PTPN6 TLR1 TLR2 TRIM54
Entrez ID		2529	81793
HPRD ID		03611	05884
Ensembl ID		ENSG00000180549	ENSG00000174123
Uniprot IDs		Q11130	A0A024R9W4 Q9BXR5
PDB IDs			2J67
Enriched GO Terms of Interacting Partners?
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