PDCD1LG2 and TMEM147

Data Source:
BioGRID (two hybrid)

		PDCD1LG2	TMEM147
Description		programmed cell death 1 ligand 2	transmembrane protein 147
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Endomembrane System Integral Component Of Membrane	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Adaptive Immune Response Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of Activated T Cell Proliferation Cellular Response To Lipopolysaccharide
Pathways		PD-1 signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269)
Interacting Genes		20 interacting genes: ATP6V0C ERMP1 GALNT15 GPR37L1 KTN1 LRP10 MFSD6 PDCD1 RUSF1 SLC35C2 SLC38A1 SLC38A7 SLC41A2 SLC7A1 SMIM3 TAS2R10 TMEM147 TMEM218 TMEM239 TMEM97	54 interacting genes: ABHD16A ABI3 CD40 CD79A CLDN7 CLN8 CLRN1 CREB3L1 CXCR2 DPM3 EBP EFNA4 ENPP4 F11R FFAR2 GJA8 GLP1R GOLM1 GPR101 GPR37L1 GPR42 GPR61 HTR2C IL3RA KASH5 LDLRAD1 LEUTX LHFPL2 MTIF3 MUC1 PACC1 PDCD1LG2 PSCA PVR RMDN3 RNF185 SCAMP4 SHISA3 SLC10A1 SLC12A7 SLC13A4 SLC22A1 SLC22A2 SUSD3 SYNE4 TACR1 TEX29 TMEM14B TMEM237 TMEM248 TMEM252 TMEM42 TMEM52B TSPAN12
Entrez ID		80380	10430
HPRD ID		16147	17633
Ensembl ID		ENSG00000197646	ENSG00000105677
Uniprot IDs		Q9BQ51	Q9BVK8
PDB IDs		6UMT	6W6L
Enriched GO Terms of Interacting Partners?
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