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PDCD1LG2 and ERMP1
Data Source:
BioGRID
(two hybrid)
PDCD1LG2
ERMP1
Description
programmed cell death 1 ligand 2
endoplasmic reticulum metallopeptidase 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Plasma Membrane
External Side Of Plasma Membrane
Endomembrane System
Integral Component Of Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Molecular_function
Protein Binding
Protein Binding
Metallopeptidase Activity
Metal Ion Binding
Biological Process
Adaptive Immune Response
Immune Response
Cell Surface Receptor Signaling Pathway
T Cell Costimulation
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-10 Production
Positive Regulation Of T Cell Proliferation
Negative Regulation Of T Cell Proliferation
Negative Regulation Of Activated T Cell Proliferation
Cellular Response To Lipopolysaccharide
Proteolysis
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Oxidative Stress
Pathways
PD-1 signaling
Drugs
Diseases
GWAS
Blood protein levels (
30072576
29875488
28240269
)
Asthma (
31959851
31619474
)
Blond vs. brown/black hair color (
30531825
)
Waist-hip ratio (
28552196
)
Interacting Genes
20 interacting genes:
ATP6V0C
ERMP1
GALNT15
GPR37L1
KTN1
LRP10
MFSD6
PDCD1
RUSF1
SLC35C2
SLC38A1
SLC38A7
SLC41A2
SLC7A1
SMIM3
TAS2R10
TMEM147
TMEM218
TMEM239
TMEM97
37 interacting genes:
AQP2
AQP6
ATP1B4
BCL2L13
BSCL2
CD200R1
CLDN5
CLDN7
CLDN9
CLEC2D
CREB3L1
ERVFRD-1
FAM209A
FNDC9
GJA8
GPR42
GPRC5D
HHLA2
HIBADH
IER3IP1
IFNGR2
KCNN3
KLRC1
LYPD5
MR1
PDCD1LG2
PEX12
RHCG
SLC13A4
SLC22A23
SLC23A2
SLC7A14
SPAG4
SSMEM1
TMEM237
TMEM45A
TMEM80
Entrez ID
80380
79956
HPRD ID
16147
17227
Ensembl ID
ENSG00000197646
ENSG00000099219
Uniprot IDs
Q9BQ51
Q6ZMD3
Q7Z2K6
PDB IDs
6UMT
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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