PSCA and TMEM86B

Data Source:
BioGRID (two hybrid)

		PSCA	TMEM86B
Description		prostate stem cell antigen	transmembrane protein 86B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Acetylcholine Receptor Binding	Protein Binding Ether Hydrolase Activity Identical Protein Binding Alkenylglycerophosphocholine Hydrolase Activity Alkenylglycerophosphoethanolamine Hydrolase Activity
	Biological Process	Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Neurotransmitter Receptor Activity	Phosphatidylcholine Acyl-chain Remodeling Ether Lipid Metabolic Process
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Acyl chain remodelling of PC
Drugs
Diseases
GWAS		Bladder cancer ( 32117775 24163127 20972438 19648920) Blood urea nitrogen levels ( 31152163) Duodenal ulcer ( 22387998) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric atrophy ( 30753327) Gastric cancer ( 30189721 26098866) Non-cardia gastric cancer ( 26701879) Optic disc size ( 31809533) Pepsinogen I/II ratio ( 30753327) Severe gastric atrophy ( 30753327) Urinary tract infection frequency ( 28928442) Vertical cup-disc ratio ( 28073927)	Mean reticulocyte volume ( 32888494) Phosphatidylethanolamine-ether levels ( 31551469) Systemic lupus erythematosus ( 33536424 28714469)
Interacting Genes		43 interacting genes: AGPAT5 AIG1 APOA2 APOL2 BCL2L2 BRICD5 CD53 CDIPT CMTM5 CTSA CYB561D2 DERL3 ERG28 INSIG2 JAGN1 LAT MOSPD3 PLP2 PLPP4 RUSF1 SLC16A4 SLC30A8 SLC35A1 SLC7A1 SMIM3 ST6GAL2 STX8 SYS1 TMEM140 TMEM147 TMEM218 TMEM239 TMEM243 TMEM262 TMEM42 TMEM54 TMEM86B TMEM97 TRARG1 TSPO2 UNC93A VAMP4 YIPF6	105 interacting genes: AQP6 ARL13B ARL6IP6 ASGR2 BCL2L13 BIK BMP10 C2CD2L CCDC167 CCDC34 CCL4 CD53 CD79A CLRN1 CYB5B DHRSX DNAJC30 EBP ERGIC3 ERP29 EVI2B F11R FAM209A FAXDC2 FKBP7 FXYD6 GJA1 GJA4 GJA8 GOLM1 GPR37L1 GPX8 GUCA2A HIBADH HSD17B13 IER3IP1 IFITM3 KIR2DL3 LAPTM4B LIME1 LSS LY6D MARCHF2 MFF MGST3 MMGT1 MS4A14 MSMO1 MUC1 NDUFAF1 NEMP1 NINJ2 ORMDL2 OTULINL PEX11G PGRMC2 PIGF PLN PSCA PTPN1 PTPN9 RHBDD1 RHOT2 RPRM RTP2 SEC22B SERINC2 SFRP1 SFT2D1 SFXN5 SLC10A6 SLC29A2 SLC35G2 SLC39A9 SMIM1 SNORC SSMEM1 STOM STX12 STX6 STX8 TEX29 THAP4 THBD TIMM23 TMEM106A TMEM107 TMEM120A TMEM14A TMEM14C TMEM203 TMEM237 TMEM248 TMEM52B TMEM60 TMPRSS2 TMX2 TREX1 TSNARE1 USE1 VAMP2 VAMP3 VAMP5 VAPA ZDHHC22
Entrez ID		8000	255043
HPRD ID		03919	14540
Ensembl ID		ENSG00000167653	ENSG00000180089
Uniprot IDs		D3DWI6 O43653	Q8N661
PDB IDs
Enriched GO Terms of Interacting Partners?
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