NUDT18 and DUT

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NUDT18	DUT
Description		nudix hydrolase 18	deoxyuridine triphosphatase
Image
GO Annotations	Cellular Component	Cytosol	Nucleus Nucleoplasm Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Protein Binding 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity	Magnesium Ion Binding RNA Binding DUTP Diphosphatase Activity Protein Binding Receptor Inhibitor Activity Pyrimidine Deoxyribonucleotide Binding Identical Protein Binding Peroxisome Proliferator Activated Receptor Binding
	Biological Process	Nucleobase-containing Small Molecule Catabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process	Liver Development Nucleobase-containing Compound Metabolic Process DUMP Biosynthetic Process DNA Replication Response To Organic Cyclic Compound Nucleobase-containing Small Molecule Interconversion Regulation Of Protein-containing Complex Assembly DUTP Catabolic Process Negative Regulation Of Signaling Receptor Activity
Pathways
Drugs			Deoxyuridine-5'-Diphosphate 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS			Blood protein levels ( 30072576) Height ( 31562340) Protein quantitative trait loci ( 18464913) Skin pigmentation ( 28300201)
Interacting Genes		34 interacting genes: APIP CAVIN2 COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1	9 interacting genes: CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2
Entrez ID		79873	1854
HPRD ID		07992	03165
Ensembl ID		ENSG00000275074	ENSG00000128951
Uniprot IDs		Q6ZVK8	A0A0C4DGL3 H0YNW5 P33316
PDB IDs		3GG6 4HVY	1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4MZ5 4MZ6 5H4J
Enriched GO Terms of Interacting Partners?
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