DUT and ESRRA

Data Source:
HPRD (two hybrid)

		DUT	ESRRA
Description		deoxyuridine triphosphatase	estrogen related receptor alpha
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Cytosol Extracellular Exosome	Chromatin Fibrillar Center Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	Magnesium Ion Binding RNA Binding DUTP Diphosphatase Activity Protein Binding Receptor Inhibitor Activity Pyrimidine Deoxyribonucleotide Binding Identical Protein Binding Peroxisome Proliferator Activated Receptor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Nuclear Receptor Activity Steroid Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Liver Development Nucleobase-containing Compound Metabolic Process DUMP Biosynthetic Process DNA Replication Response To Organic Cyclic Compound Nucleobase-containing Small Molecule Interconversion Regulation Of Protein-containing Complex Assembly DUTP Catabolic Process Negative Regulation Of Signaling Receptor Activity	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Mitochondrion Organization Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II
Pathways			PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis Nuclear Receptor transcription pathway Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity
Drugs		Deoxyuridine-5'-Diphosphate 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE	Troglitazone Diethylstilbestrol Genistein Afimoxifene beta-Naphthoflavone 1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE Flavone
Diseases
GWAS		Blood protein levels ( 30072576) Height ( 31562340) Protein quantitative trait loci ( 18464913) Skin pigmentation ( 28300201)	Crohn's disease ( 28067908 21102463) Vitiligo ( 27723757)
Interacting Genes		9 interacting genes: CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2	36 interacting genes: ADH5 ATXN1 DUT ESR1 ESRRG EXOSC6 FAM9A FUS GTF2B HDAC8 HIF1A KAT2B LYST MACF1 MAP2K5 NCOA1 NCOA3 NR0B1 NR0B2 NRIP1 NSD1 NXF1 PIAS4 PNRC2 PPARG PPARGC1A PRKCD PROX1 PSMC5 REL RNF4 RXRA SIRT1 SMARCD3 SP1 TNNI2
Entrez ID		1854	2101
HPRD ID		03165	07210
Ensembl ID		ENSG00000128951	ENSG00000173153
Uniprot IDs		A0A0C4DGL3 H0YNW5 P33316	P11474 Q569H8
PDB IDs		1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4MZ5 4MZ6 5H4J	1XB7 2PJL 3D24 3K6P
Enriched GO Terms of Interacting Partners?
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