NUDT18 and GNMT

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NUDT18	GNMT
Description		nudix hydrolase 18	glycine N-methyltransferase
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GO Annotations	Cellular Component	Cytosol	Cytosol
	Molecular Function	Magnesium Ion Binding Protein Binding 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity	Protein Binding Folic Acid Binding Glycine Binding Glycine N-methyltransferase Activity Identical Protein Binding S-adenosyl-L-methionine Binding
	Biological Process	Nucleobase-containing Small Molecule Catabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process	Glycogen Metabolic Process Regulation Of Gluconeogenesis Cellular Protein Modification Process Methionine Metabolic Process One-carbon Metabolic Process Methylation Cellular Nitrogen Compound Metabolic Process S-adenosylhomocysteine Metabolic Process S-adenosylmethionine Metabolic Process Protein Homotetramerization Sarcosine Metabolic Process
Pathways			Metabolism of ingested SeMet, Sec, MeSec into H2Se Glyoxylate metabolism and glycine degradation
Drugs			Ademetionine Glycine S-adenosyl-L-homocysteine
Diseases			Hypermethioninemia; Methionine adenosyltransferase deficiency; S-adenosylhomocysteine hydrolase deficiency
GWAS			Apolipoprotein B levels ( 32203549) Blood protein levels ( 30072576 29875488) LDL cholesterol levels ( 32203549) Plasma homocysteine levels (post-methionine load test) ( 24651765)
Interacting Genes		34 interacting genes: APIP CAVIN2 COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1	30 interacting genes: ADAMTSL4 ARR3 ARRB1 CCDC153 COX7B CTNS FRG1 GABRQ GAGE2A HDAC7 HPRT1 KRTAP10-3 KRTAP4-2 NIF3L1 NOTCH2NLA NTAQ1 NUDT18 PLEKHF2 POT1 PRKACA RPSA SDCBP SNRNP200 SRD5A2 TERF1 TERF2 TERF2IP TINF2 TRIM35 ZNF337
Entrez ID		79873	27232
HPRD ID		07992	05970
Ensembl ID		ENSG00000275074	ENSG00000124713
Uniprot IDs		Q6ZVK8	A0A0S2Z5F2 Q14749 V9HW60
PDB IDs		3GG6 4HVY	1R74 2AZT
Enriched GO Terms of Interacting Partners?
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