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DUT and NUDT18
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
DUT
NUDT18
Description
deoxyuridine triphosphatase
nudix hydrolase 18
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Mitochondrion
Cytosol
Extracellular Exosome
Cytosol
Molecular Function
Magnesium Ion Binding
RNA Binding
DUTP Diphosphatase Activity
Protein Binding
Receptor Inhibitor Activity
Pyrimidine Deoxyribonucleotide Binding
Identical Protein Binding
Peroxisome Proliferator Activated Receptor Binding
Magnesium Ion Binding
Protein Binding
8-oxo-dGDP Phosphatase Activity
8-oxo-GDP Phosphatase Activity
8-hydroxy-dADP Phosphatase Activity
Biological Process
Liver Development
Nucleobase-containing Compound Metabolic Process
DUMP Biosynthetic Process
DNA Replication
Response To Organic Cyclic Compound
Nucleobase-containing Small Molecule Interconversion
Regulation Of Protein-containing Complex Assembly
DUTP Catabolic Process
Negative Regulation Of Signaling Receptor Activity
Nucleobase-containing Small Molecule Catabolic Process
DADP Catabolic Process
DGDP Catabolic Process
GDP Catabolic Process
Pathways
Drugs
Deoxyuridine-5'-Diphosphate
1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS
Blood protein levels (
30072576
)
Height (
31562340
)
Protein quantitative trait loci (
18464913
)
Skin pigmentation (
28300201
)
Interacting Genes
9 interacting genes:
CDK1
ESR1
ESRRA
ESRRG
NUDT18
PLEKHF2
PPARA
PPARD
SPATA2
34 interacting genes:
APIP
CAVIN2
COIL
CUTC
DCTD
DHPS
DUT
EVI5L
GLUL
GNMT
GSE1
HSD17B14
KCTD13
KCTD17
KHDRBS3
KRT15
KRTAP4-12
KXD1
NADK
NAT9
NT5C2
PAICS
PCBD1
PSME3
RAB3IL1
RABAC1
RAD54B
RWDD1
TARBP2
TERF2IP
TIFA
TRAF2
TRIM37
ZBED1
Entrez ID
1854
79873
HPRD ID
03165
07992
Ensembl ID
ENSG00000128951
ENSG00000275074
Uniprot IDs
A0A0C4DGL3
H0YNW5
P33316
Q6ZVK8
PDB IDs
1Q5H
1Q5U
2HQU
3ARA
3ARN
3EHW
4MZ5
4MZ6
5H4J
3GG6
4HVY
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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