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DERL1 and TEX44
Data Source:
BioGRID
(two hybrid)
DERL1
TEX44
Description
derlin 1
testis expressed 44
Image
No pdb structure
GO Annotations
Cellular Component
Hrd1p Ubiquitin Ligase ERAD-L Complex
Early Endosome
Late Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Derlin-1-VIMP Complex
Derlin-1 Retrotranslocation Complex
Endoplasmic Reticulum Quality Control Compartment
Cytoplasm
Molecular Function
Protease Binding
Signal Recognition Particle Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Signaling Receptor Activity
MHC Class I Protein Binding
Identical Protein Binding
Protein-containing Complex Binding
ATPase Binding
Misfolded Protein Binding
Ubiquitin-specific Protease Binding
Protein Binding
Biological Process
Protein Folding
Response To Unfolded Protein
Viral Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Endoplasmic Reticulum Unfolded Protein Response
Retrograde Protein Transport, ER To Cytosol
Positive Regulation Of Protein Ubiquitination
Protein Destabilization
Positive Regulation Of Protein Binding
ERAD Pathway
Establishment Of Protein Localization
Transmembrane Transport
ER-associated Misfolded Protein Catabolic Process
Pathways
ABC-family proteins mediated transport
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Defective CFTR causes cystic fibrosis
E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Mean reticulocyte volume (
32888494
)
Metabolite levels (
23823483
)
Interacting Genes
33 interacting genes:
ABHD4
AMFR
APP
AQP6
CFTR
CIAO2A
FCRL4
FFAR2
GAD2
HLA-A
KASH5
LMNA
LNX1
MELTF
REEP4
RETREG3
RHO
SCN3B
SELENOS
SLC10A1
SLC10A6
SLC30A8
SLC7A14
SLC7A8
TCF25
TEX44
TMED8
TMEM31
TMX2
TRIM32
UBE2J1
UBXN6
VCP
13 interacting genes:
APOC1
APP
C3orf33
CIDEB
COX20
CPT1B
DERL1
MICOS13
MPC2
RHBDD2
SYPL1
TIMM17B
TMEM14B
Entrez ID
79139
165100
HPRD ID
12302
14602
Ensembl ID
ENSG00000136986
ENSG00000177673
Uniprot IDs
A0A024R9G3
E5RGY0
Q9BUN8
Q53QW1
PDB IDs
5GLF
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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