TEX44 and DERL1

Data Source:
BioGRID (two hybrid)

		TEX44	DERL1
Description		testis expressed 44	derlin 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Hrd1p Ubiquitin Ligase ERAD-L Complex Early Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Derlin-1-VIMP Complex Derlin-1 Retrotranslocation Complex Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding	Protease Binding Signal Recognition Particle Binding Protein Binding Ubiquitin Protein Ligase Binding Signaling Receptor Activity MHC Class I Protein Binding Identical Protein Binding Protein-containing Complex Binding ATPase Binding Misfolded Protein Binding Ubiquitin-specific Protease Binding
	Biological Process		Protein Folding Response To Unfolded Protein Viral Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Positive Regulation Of Protein Ubiquitination Protein Destabilization Positive Regulation Of Protein Binding ERAD Pathway Establishment Of Protein Localization Transmembrane Transport ER-associated Misfolded Protein Catabolic Process
Pathways			ABC-family proteins mediated transport N-glycan trimming in the ER and Calnexin/Calreticulin cycle Defective CFTR causes cystic fibrosis E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS			Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: APOC1 APP C3orf33 CIDEB COX20 CPT1B DERL1 MICOS13 MPC2 RHBDD2 SYPL1 TIMM17B TMEM14B	33 interacting genes: ABHD4 AMFR APP AQP6 CFTR CIAO2A FCRL4 FFAR2 GAD2 HLA-A KASH5 LMNA LNX1 MELTF REEP4 RETREG3 RHO SCN3B SELENOS SLC10A1 SLC10A6 SLC30A8 SLC7A14 SLC7A8 TCF25 TEX44 TMED8 TMEM31 TMX2 TRIM32 UBE2J1 UBXN6 VCP
Entrez ID		165100	79139
HPRD ID		14602	12302
Ensembl ID		ENSG00000177673	ENSG00000136986
Uniprot IDs		Q53QW1	A0A024R9G3 E5RGY0 Q9BUN8
PDB IDs			5GLF
Enriched GO Terms of Interacting Partners?
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