VIM and ANXA7

Data Source:
BioGRID (two hybrid)

		VIM	ANXA7
Description		vimentin	annexin A7
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisome Cytosol Polysome Cytoskeleton Intermediate Filament Plasma Membrane Focal Adhesion Nuclear Matrix Cell Leading Edge Neuron Projection Intermediate Filament Cytoskeleton Phagocytic Vesicle Extracellular Exosome Ribonucleoprotein Complex	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Membrane Chromaffin Granule Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Double-stranded RNA Binding Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding Protein Domain Specific Binding Identical Protein Binding Scaffold Protein Binding Keratin Filament Binding	RNA Binding Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Calcium-dependent Protein Binding
	Biological Process	Negative Regulation Of Neuron Projection Development Astrocyte Development Viral Process Cytokine-mediated Signaling Pathway Muscle Filament Sliding Positive Regulation Of Collagen Biosynthetic Process Regulation Of MRNA Stability Intermediate Filament Organization Positive Regulation Of Translation Bergmann Glial Cell Differentiation SMAD Protein Signal Transduction Lens Fiber Cell Development Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Cellular Response To Interferon-gamma	Autophagy Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Epithelial Cell Differentiation Response To Calcium Ion Membrane Fusion
Pathways		Caspase-mediated cleavage of cytoskeletal proteins Striated Muscle Contraction Interleukin-4 and Interleukin-13 signaling Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy
Drugs		Artenimol Phenethyl Isothiocyanate
Diseases
GWAS		Cholesterol, total ( 24097068) HDL cholesterol levels ( 32203549) Mean spheric corpuscular volume ( 32888494) Total cholesterol levels ( 28334899) Triglyceride levels ( 32203549)	Copper levels ( 26025379)
Interacting Genes		171 interacting genes: ABLIM1 AKT1 ANKRD35 ANXA7 APIP APLP1 APP ARMC7 ARMCX2 ATN1 BFSP1 BHLHE40 BRD1 BYSL C2CD6 CAMK2D CAPN1 CASP3 CASP6 CASP7 CASP8 CASP9 CBX8 CCDC187 CDH5 CDK1 CDKN1A CEP126 CHD3 COPS6 CRCT1 CREB1 CRMP1 CT55 CWF19L2 DCTN1 DEFB1 DES DIS3L2 DNM1L DPPA4 DSP DUX4 DYNLL1 ENTR1 ESS2 FABP4 FAM107A FAM118B FAM161A FUBP1 GADD45A GEM GFAP GOPC GRB2 GSK3B HABP4 HAP1 HMG20B HSPB1 HTRA2 ING5 IP6K1 ITGB4 IVNS1ABP KARS1 KAT7 KIAA0408 KIF15 KIF9 KIFC3 KRT20 KRT75 LGALS14 LINC01554 LORICRIN LRIF1 MAFG MAN2A2 MCPH1 MEN1 MICAL1 MRPL44 MTDH NEFL NEFM NFATC2 NFKBID NIF3L1 NME2 NOC4L NR1H2 NUP85 OSBP2 PAK2 PDLIM1 PIAS4 PKD1 PKN1 PKP1 PLA2G2A PLA2G4A PLEC PNMA5 POLR1C PPHLN1 PPL PPP1R18 PRKACA PRPH PSMA1 PSMC5 PSMD7 PSME1 PUF60 RAB8B RABAC1 RAD51 RBM48 RIBC2 ROCK1 RPA1 SCNM1 SERBP1 SETDB1 SH3GL1 SH3GL3 SH3YL1 SIRPA SIRT6 SLC25A6 SLC27A6 SMAD3 SMARCB1 SRRT STK19 STX1A SUMO2 SUMO3 SYN1 TAB2 TCEA2 TCHP TLE5 TNFRSF14 TNNT1 TRIM14 TRIM15 TRIM28 TRIM29 TRIOBP TSC22D1 TTR TUBA1C TUBGCP4 TXLNB TXN TXN2 UPP1 UPP2 UROD UTP14A WBP11 XRCC4 YAE1 YWHAE YWHAZ ZHX1 ZNF384 ZNF572	107 interacting genes: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5F1B ATP6V1A ATXN3 BAG6 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 ERG28 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 INPP5K INTS11 KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS1 RBBP4 RBM48 RPA1 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		7431	310
HPRD ID		01899	01720
Ensembl ID		ENSG00000026025	ENSG00000138279
Uniprot IDs		P08670 V9HWE1	B2R657 P20073
PDB IDs		1GK4 1GK6 1GK7 3G1E 3KLT 3S4R 3SSU 3SWK 3TRT 3UF1 4MCY 4MCZ 4MD0 4MD5 4MDI 4MDJ 4YPC 4YV3 5WHF 6ATF 6ATI 6BIR
Enriched GO Terms of Interacting Partners?
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