VIM and FABP4

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		VIM	FABP4
Description		vimentin	fatty acid binding protein 4
Image
GO Annotations	Cellular Component	Cytoplasm Peroxisome Cytosol Polysome Cytoskeleton Intermediate Filament Plasma Membrane Focal Adhesion Nuclear Matrix Cell Leading Edge Neuron Projection Intermediate Filament Cytoskeleton Phagocytic Vesicle Extracellular Exosome Ribonucleoprotein Complex	Nucleus Cytoplasm Lipid Droplet Cytosol Extracellular Exosome
	Molecular Function	Double-stranded RNA Binding Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding Protein Domain Specific Binding Identical Protein Binding Scaffold Protein Binding Keratin Filament Binding	Long-chain Fatty Acid Transporter Activity Fatty Acid Binding Long-chain Fatty Acid Binding Hormone Receptor Binding
	Biological Process	Negative Regulation Of Neuron Projection Development Astrocyte Development Viral Process Cytokine-mediated Signaling Pathway Muscle Filament Sliding Positive Regulation Of Collagen Biosynthetic Process Regulation Of MRNA Stability Intermediate Filament Organization Positive Regulation Of Translation Bergmann Glial Cell Differentiation SMAD Protein Signal Transduction Lens Fiber Cell Development Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Cellular Response To Interferon-gamma	Negative Regulation Of Protein Kinase Activity Response To Bacterium Long-chain Fatty Acid Transport Triglyceride Catabolic Process Cholesterol Homeostasis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Inflammatory Response White Fat Cell Differentiation Brown Fat Cell Differentiation Cellular Response To Lithium Ion Cellular Response To Tumor Necrosis Factor Positive Regulation Of Cold-induced Thermogenesis
Pathways		Caspase-mediated cleavage of cytoskeletal proteins Striated Muscle Contraction Interleukin-4 and Interleukin-13 signaling Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy	Triglyceride catabolism Triglyceride catabolism Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs		Artenimol Phenethyl Isothiocyanate
Diseases
GWAS		Cholesterol, total ( 24097068) HDL cholesterol levels ( 32203549) Mean spheric corpuscular volume ( 32888494) Total cholesterol levels ( 28334899) Triglyceride levels ( 32203549)	Blood protein levels ( 30072576) Metabolite levels ( 23823483) Ovarian cancer ( 23535730) Visceral fat ( 22589738)
Interacting Genes		171 interacting genes: ABLIM1 AKT1 ANKRD35 ANXA7 APIP APLP1 APP ARMC7 ARMCX2 ATN1 BFSP1 BHLHE40 BRD1 BYSL C2CD6 CAMK2D CAPN1 CASP3 CASP6 CASP7 CASP8 CASP9 CBX8 CCDC187 CDH5 CDK1 CDKN1A CEP126 CHD3 COPS6 CRCT1 CREB1 CRMP1 CT55 CWF19L2 DCTN1 DEFB1 DES DIS3L2 DNM1L DPPA4 DSP DUX4 DYNLL1 ENTR1 ESS2 FABP4 FAM107A FAM118B FAM161A FUBP1 GADD45A GEM GFAP GOPC GRB2 GSK3B HABP4 HAP1 HMG20B HSPB1 HTRA2 ING5 IP6K1 ITGB4 IVNS1ABP KARS1 KAT7 KIAA0408 KIF15 KIF9 KIFC3 KRT20 KRT75 LGALS14 LINC01554 LORICRIN LRIF1 MAFG MAN2A2 MCPH1 MEN1 MICAL1 MRPL44 MTDH NEFL NEFM NFATC2 NFKBID NIF3L1 NME2 NOC4L NR1H2 NUP85 OSBP2 PAK2 PDLIM1 PIAS4 PKD1 PKN1 PKP1 PLA2G2A PLA2G4A PLEC PNMA5 POLR1C PPHLN1 PPL PPP1R18 PRKACA PRPH PSMA1 PSMC5 PSMD7 PSME1 PUF60 RAB8B RABAC1 RAD51 RBM48 RIBC2 ROCK1 RPA1 SCNM1 SERBP1 SETDB1 SH3GL1 SH3GL3 SH3YL1 SIRPA SIRT6 SLC25A6 SLC27A6 SMAD3 SMARCB1 SRRT STK19 STX1A SUMO2 SUMO3 SYN1 TAB2 TCEA2 TCHP TLE5 TNFRSF14 TNNT1 TRIM14 TRIM15 TRIM28 TRIM29 TRIOBP TSC22D1 TTR TUBA1C TUBGCP4 TXLNB TXN TXN2 UPP1 UPP2 UROD UTP14A WBP11 XRCC4 YAE1 YWHAE YWHAZ ZHX1 ZNF384 ZNF572	8 interacting genes: ACP1 ACTB CHD3 INSR LIPE PRKCI VIM ZBED1
Entrez ID		7431	2167
HPRD ID		01899	02698
Ensembl ID		ENSG00000026025	ENSG00000170323
Uniprot IDs		P08670 V9HWE1	E7DVW4 P15090
PDB IDs		1GK4 1GK6 1GK7 3G1E 3KLT 3S4R 3SSU 3SWK 3TRT 3UF1 4MCY 4MCZ 4MD0 4MD5 4MDI 4MDJ 4YPC 4YV3 5WHF 6ATF 6ATI 6BIR	1TOU 1TOW 2HNX 2NNQ 3FR2 3FR4 3FR5 3P6C 3P6D 3P6E 3P6F 3P6G 3P6H 3Q6L 3RZY 4NNS 4NNT 5D45 5D47 5D48 5D4A 5EDB 5EDC 5HZ6 5HZ8 5Y0F 5Y0G 5Y0X 5Y12 5Y13 6AYL 6LJS 6LJT 6LJU 6LJV 6LJW 6LJX
Enriched GO Terms of Interacting Partners?
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