TSHB and CGA

Data Source:
HPRD (in vivo)

		TSHB	CGA
Description		thyroid stimulating hormone subunit beta	glycoprotein hormones, alpha polypeptide
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Extracellular Region Extracellular Space Golgi Lumen Follicle-stimulating Hormone Complex
	Molecular Function	Hormone Activity	Hormone Activity Protein Binding Follicle-stimulating Hormone Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Anatomical Structure Morphogenesis Hormone-mediated Signaling Pathway Peptide Hormone Processing Response To Vitamin A Response To Estrogen Response To Calcium Ion	Regulation Of Transcription By RNA Polymerase II Thyroid Hormone Generation G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Regulation Of Signaling Receptor Activity Positive Regulation Of Steroid Biosynthetic Process Peptide Hormone Processing Positive Regulation Of Cell Migration Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Glycoprotein hormones Thyroxine biosynthesis Hormone ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Androgen biosynthesis Mineralocorticoid biosynthesis Glycoprotein hormones Thyroxine biosynthesis Hormone ligand-binding receptors G alpha (s) signalling events TFAP2 (AP-2) family regulates transcription of growth factors and their receptors ADORA2B mediated anti-inflammatory cytokines production Reactions specific to the complex N-glycan synthesis pathway
Drugs
Diseases		Congenital nongoitrous hypothyroidism (CHNG)
GWAS		California verbal learning test score ( 31596458)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Atrial fibrillation ( 30061737 29892015) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		2 interacting genes: CGA TSHR	9 interacting genes: CGB3 CGB5 FSHB FSHR LHB LHCGR PTN PTPN12 TSHB
Entrez ID		7252	1081
HPRD ID		11766	00342
Ensembl ID		ENSG00000134200	ENSG00000135346
Uniprot IDs		P01222	A0A087WYZ4 P01215 Q6I9S8
PDB IDs			1DZ7 1E9J 1FL7 1HCN 1HD4 1HRP 1QFW 1XUL 1XWD 4AY9 4MQW
Enriched GO Terms of Interacting Partners?
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