CGA and TSHB

Data Source:
HPRD (in vivo)

		CGA	TSHB
Description		glycoprotein hormones, alpha polypeptide	thyroid stimulating hormone subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen Follicle-stimulating Hormone Complex	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Hormone Activity Protein Binding Follicle-stimulating Hormone Activity	Hormone Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Thyroid Hormone Generation G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Regulation Of Signaling Receptor Activity Positive Regulation Of Steroid Biosynthetic Process Peptide Hormone Processing Positive Regulation Of Cell Migration Positive Regulation Of Transcription By RNA Polymerase II	G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Anatomical Structure Morphogenesis Hormone-mediated Signaling Pathway Peptide Hormone Processing Response To Vitamin A Response To Estrogen Response To Calcium Ion
Pathways		Androgen biosynthesis Mineralocorticoid biosynthesis Glycoprotein hormones Thyroxine biosynthesis Hormone ligand-binding receptors G alpha (s) signalling events TFAP2 (AP-2) family regulates transcription of growth factors and their receptors ADORA2B mediated anti-inflammatory cytokines production Reactions specific to the complex N-glycan synthesis pathway	Glycoprotein hormones Thyroxine biosynthesis Hormone ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases			Congenital nongoitrous hypothyroidism (CHNG)
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Atrial fibrillation ( 30061737 29892015) Thyroid stimulating hormone levels ( 32769997)	California verbal learning test score ( 31596458)
Interacting Genes		9 interacting genes: CGB3 CGB5 FSHB FSHR LHB LHCGR PTN PTPN12 TSHB	2 interacting genes: CGA TSHR
Entrez ID		1081	7252
HPRD ID		00342	11766
Ensembl ID		ENSG00000135346	ENSG00000134200
Uniprot IDs		A0A087WYZ4 P01215 Q6I9S8	P01222
PDB IDs		1DZ7 1E9J 1FL7 1HCN 1HD4 1HRP 1QFW 1XUL 1XWD 4AY9 4MQW
Enriched GO Terms of Interacting Partners?
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