CGA and LHB

Data Source:
HPRD (in vivo, in vitro)

		CGA	LHB
Description		glycoprotein hormones, alpha polypeptide	luteinizing hormone subunit beta
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen Follicle-stimulating Hormone Complex	Extracellular Region Extracellular Space Cytoplasm Golgi Lumen
	Molecular Function	Hormone Activity Protein Binding Follicle-stimulating Hormone Activity	Signaling Receptor Binding Hormone Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Thyroid Hormone Generation G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Regulation Of Signaling Receptor Activity Positive Regulation Of Steroid Biosynthetic Process Peptide Hormone Processing Positive Regulation Of Cell Migration Positive Regulation Of Transcription By RNA Polymerase II	Progesterone Biosynthetic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Male Gonad Development Hormone-mediated Signaling Pathway Peptide Hormone Processing
Pathways		Androgen biosynthesis Mineralocorticoid biosynthesis Glycoprotein hormones Thyroxine biosynthesis Hormone ligand-binding receptors G alpha (s) signalling events TFAP2 (AP-2) family regulates transcription of growth factors and their receptors ADORA2B mediated anti-inflammatory cytokines production Reactions specific to the complex N-glycan synthesis pathway	Androgen biosynthesis Mineralocorticoid biosynthesis Glycoprotein hormones Hormone ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production Reactions specific to the complex N-glycan synthesis pathway
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Atrial fibrillation ( 30061737 29892015) Thyroid stimulating hormone levels ( 32769997)	Blood protein levels ( 29875488 28240269)
Interacting Genes		9 interacting genes: CGB3 CGB5 FSHB FSHR LHB LHCGR PTN PTPN12 TSHB	7 interacting genes: CGA FHL3 GNAI2 GNAS LHCGR NTM SGTB
Entrez ID		1081	3972
HPRD ID		00342	01072
Ensembl ID		ENSG00000135346	ENSG00000104826
Uniprot IDs		A0A087WYZ4 P01215 Q6I9S8	A0A0F7RQE6 P01229
PDB IDs		1DZ7 1E9J 1FL7 1HCN 1HD4 1HRP 1QFW 1XUL 1XWD 4AY9 4MQW	1M92
Enriched GO Terms of Interacting Partners?
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