Description |
DNA topoisomerase I |
RB transcriptional corepressor like 2 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
- Antipsychotic drug-induced weight gain in schizophrenia ( 31447353)
- Brain morphology (MOSTest) ( 32665545)
- Cholesterol, total ( 24097068 20686565)
- Hemoglobin ( 32888494)
- LDL cholesterol ( 24097068 20686565)
- LDL cholesterol levels ( 28334899)
- LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
- LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
- Male-pattern baldness ( 28196072)
- Metabolite levels ( 23823483)
- PR interval ( 32439900)
- Red blood cell count ( 32888494)
- Refractive error ( 32231278)
- Total cholesterol levels ( 28334899)
- Urate levels ( 31578528)
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Interacting Genes |
60 interacting genes:
APAF1
APP
ATM
BARD1
BRCA1
BRD2
BTBD1
BTBD2
BUB3
CASP3
CASP6
CDK8
CKAP5
CSNK2A1
CSNK2A2
DDB2
ELK3
ERCC8
ERG
FSHR
GEMIN4
IL7R
IRF4
IRF8
IRF9
JAK1
JUN
KMT2A
LIG4
LSM4
MDM2
NCL
NCOA6
PDE10A
PPP2R2B
PRB1
PRKDC
PYGM
RBL1
RBL2
RCVRN
SF3B1
SFPQ
SNRNP70
SNW1
SRPK2
SRSF1
SRSF11
SUMO1
SYMPK
TARBP2
TDP1
TOPORS
TP53
TRIM32
TUBD1
U2AF2
UBE2I
XRCC5
XRCC6
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44 interacting genes:
BRCA1
BRF1
BRF2
CCNA1
CCNA2
CCND1
CCND3
CCNE1
CDK2
CDK4
CDK6
CREG1
DCTN1
DGKZ
E2F4
E2F5
EZH2
GRAMD4
HBP1
HDAC1
ID2
KMT5C
LBX1
LDHC
LIN52
MCM7
MNDA
PCBD1
PHB
PPP2CA
RAF1
RBBP8
RBBP9
RINT1
SKP2
SMARCA4
SNW1
SUV39H1
TAF1
TOP1
TP53BP1
UBTF
USP4
XBP1
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Entrez ID |
7150 |
5934 |
HPRD ID |
00535 |
01576 |
Ensembl ID |
ENSG00000198900
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ENSG00000103479
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Uniprot IDs |
P11387
Q9BVT2
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Q08999
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PDB IDs |
1A31
1A35
1A36
1EJ9
1K4S
1K4T
1LPQ
1NH3
1R49
1RR8
1RRJ
1SC7
1SEU
1T8I
1TL8
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4XI9
5C1D
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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