Description |
DNA topoisomerase I |
X-ray repair cross complementing 5 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
- Antipsychotic drug-induced weight gain in schizophrenia ( 31447353)
- Brain morphology (MOSTest) ( 32665545)
- Cholesterol, total ( 24097068 20686565)
- Hemoglobin ( 32888494)
- LDL cholesterol ( 24097068 20686565)
- LDL cholesterol levels ( 28334899)
- LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
- LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
- Male-pattern baldness ( 28196072)
- Metabolite levels ( 23823483)
- PR interval ( 32439900)
- Red blood cell count ( 32888494)
- Refractive error ( 32231278)
- Total cholesterol levels ( 28334899)
- Urate levels ( 31578528)
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Interacting Genes |
60 interacting genes:
APAF1
APP
ATM
BARD1
BRCA1
BRD2
BTBD1
BTBD2
BUB3
CASP3
CASP6
CDK8
CKAP5
CSNK2A1
CSNK2A2
DDB2
ELK3
ERCC8
ERG
FSHR
GEMIN4
IL7R
IRF4
IRF8
IRF9
JAK1
JUN
KMT2A
LIG4
LSM4
MDM2
NCL
NCOA6
PDE10A
PPP2R2B
PRB1
PRKDC
PYGM
RBL1
RBL2
RCVRN
SF3B1
SFPQ
SNRNP70
SNW1
SRPK2
SRSF1
SRSF11
SUMO1
SYMPK
TARBP2
TDP1
TOPORS
TP53
TRIM32
TUBD1
U2AF2
UBE2I
XRCC5
XRCC6
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59 interacting genes:
APEX1
AR
ATM
ATR
BAZ1A
BRCA1
CD40
CDC16
CEBPA
CHAF1A
COIL
CSNK2A1
DUX4
ELF3
ERCC6
GZMA
GZMB
HSF1
HSPB1
LIG3
LINC01554
MSX2
NAA15
NBN
NCOA6
NDRG1
ORC2
PARP1
PCNA
PDX1
PGR
POLA1
POLD1
POLE
POLR2A
PRKDC
PTEN
RBM14
RNF126
RUNX2
SGO1
SRPK2
SUMO2
SUPT4H1
SUPT5H
TCF4
TERF2IP
TERT
TOP1
TOP2B
TYK2
UBC
UBE2I
UCHL3
VAV1
WRN
XRCC6
ZBTB7A
ZRANB1
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Entrez ID |
7150 |
7520 |
HPRD ID |
00535 |
08935 |
Ensembl ID |
ENSG00000198900
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ENSG00000079246
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Uniprot IDs |
P11387
Q9BVT2
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P13010
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PDB IDs |
1A31
1A35
1A36
1EJ9
1K4S
1K4T
1LPQ
1NH3
1R49
1RR8
1RRJ
1SC7
1SEU
1T8I
1TL8
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1JEQ
1JEY
1Q2Z
1RW2
3RZ9
5Y3R
6ERF
6ERG
6ERH
6ZH6
6ZHA
6ZHE
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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