Description |
DNA topoisomerase I |
BTB domain containing 2 |
Image |
|
|
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
- Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
- Antipsychotic drug-induced weight gain in schizophrenia ( 31447353)
- Brain morphology (MOSTest) ( 32665545)
- Cholesterol, total ( 24097068 20686565)
- Hemoglobin ( 32888494)
- LDL cholesterol ( 24097068 20686565)
- LDL cholesterol levels ( 28334899)
- LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
- LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
- Male-pattern baldness ( 28196072)
- Metabolite levels ( 23823483)
- PR interval ( 32439900)
- Red blood cell count ( 32888494)
- Refractive error ( 32231278)
- Total cholesterol levels ( 28334899)
- Urate levels ( 31578528)
|
|
Interacting Genes |
60 interacting genes:
APAF1
APP
ATM
BARD1
BRCA1
BRD2
BTBD1
BTBD2
BUB3
CASP3
CASP6
CDK8
CKAP5
CSNK2A1
CSNK2A2
DDB2
ELK3
ERCC8
ERG
FSHR
GEMIN4
IL7R
IRF4
IRF8
IRF9
JAK1
JUN
KMT2A
LIG4
LSM4
MDM2
NCL
NCOA6
PDE10A
PPP2R2B
PRB1
PRKDC
PYGM
RBL1
RBL2
RCVRN
SF3B1
SFPQ
SNRNP70
SNW1
SRPK2
SRSF1
SRSF11
SUMO1
SYMPK
TARBP2
TDP1
TOPORS
TP53
TRIM32
TUBD1
U2AF2
UBE2I
XRCC5
XRCC6
|
35 interacting genes:
BRD7
CCDC90B
CCNC
CDK2
CINP
COPS6
CRMP1
CUL3
DPPA4
EEF1A1
ERG28
GAPDH
GBP2
GDF9
IGSF21
KPNA2
MLH1
NGB
NTAQ1
OSGIN1
PSMD5
PTN
RBM48
SETDB1
SMAD1
SMAD2
TDP2
TGFBR1
TLE1
TOP1
TP53
TRIM5
UBR1
UNC119
ZNF512B
|
Entrez ID |
7150 |
55643 |
HPRD ID |
00535 |
12252 |
Ensembl ID |
ENSG00000198900
|
ENSG00000133243
|
Uniprot IDs |
P11387
Q9BVT2
|
Q9BX70
|
PDB IDs |
1A31
1A35
1A36
1EJ9
1K4S
1K4T
1LPQ
1NH3
1R49
1RR8
1RRJ
1SC7
1SEU
1T8I
1TL8
|
3NO8
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|