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BUB1 and STX17
Data Source:
BioGRID
(two hybrid)
BUB1
STX17
Description
BUB1 mitotic checkpoint serine/threonine kinase
syntaxin 17
Image
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Condensed Nuclear Chromosome Kinetochore
Condensed Nuclear Chromosome Outer Kinetochore
Nucleoplasm
Cytosol
Membrane
Intracellular Membrane-bounded Organelle
Autophagosome Membrane
Mitochondrion
Lysosomal Membrane
Autophagosome
Endoplasmic Reticulum Membrane
Rough Endoplasmic Reticulum
Endoplasmic Reticulum-Golgi Intermediate Compartment
Cytosol
Plasma Membrane
Endomembrane System
ER To Golgi Transport Vesicle Membrane
Integral Component Of Membrane
COPII-coated ER To Golgi Transport Vesicle
Smooth Endoplasmic Reticulum Membrane
HOPS Complex
SNARE Complex
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Mitochondria-associated Endoplasmic Reticulum Membrane
Molecular Function
Protein Kinase Activity
Protein Binding
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
SNARE Binding
SNAP Receptor Activity
Protein Binding
Protein Kinase Binding
Protein Phosphatase Binding
Biological Process
Protein Phosphorylation
Apoptotic Process
Regulation Of Sister Chromatid Cohesion
Mitotic Cell Cycle Checkpoint
Mitotic Spindle Assembly Checkpoint
Cell Population Proliferation
Viral Process
Cell Division
Meiotic Sister Chromatid Cohesion, Centromeric
Regulation Of Chromosome Segregation
Intracellular Protein Transport
Exocytosis
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Vesicle Fusion
Golgi Organization
Autophagosome Membrane Docking
Protein Localization To Phagophore Assembly Site
Vesicle Docking
Endoplasmic Reticulum-Golgi Intermediate Compartment Organization
Autophagosome Maturation
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
COPII-mediated vesicle transport
Drugs
Diseases
GWAS
Alopecia areata (
20596022
)
Gut microbiota (bacterial taxa, rank normal transformation method) (
32572223
)
Interacting Genes
63 interacting genes:
AKT1
ALDOB
ANP32B
AOPEP
AP1B1
AP2B1
AP3B1
AP4B1
APC
ARIH2
BAAT
BUB3
CCDC180
CDC14B
CDC20
CDK1
CDK8
CORO2A
CRK
CTSV
CYLC2
DVL1
EIF4EBP1
FANCC
FBP1
FBP2
FBXO7
FRAT2
GALNT12
HDAC1
HEMGN
HRAS
HSD17B3
IGFBP3
KNL1
LEF1
MAP2K1
MAPK3
MSANTD3
NANS
PLK1
PPP2CB
PPP3R2
RAE1
RASA1
RDH12
SEC61B
SFRP2
SFRP4
SHC1
SMAD1
STX17
SVIL
TBC1D2
TDRD7
TGFB1
TMEFF1
TMOD1
TRMO
TSTD2
XPA
ZNF189
ZNF510
23 interacting genes:
ATG14
AURKA
BUB1
CDH1
CTNNA1
DLC1
EGFR
KRAS
MAP2K4
MIS18A
MLH1
MLH3
MSH2
NRAS
ODC1
PTPN12
PTPN2
RB1
SMAD4
SNAP29
SRC
STK11
TLR2
Entrez ID
699
55014
HPRD ID
03907
05013
Ensembl ID
ENSG00000169679
ENSG00000136874
Uniprot IDs
B4DYG2
O43683
P56962
PDB IDs
2LAH
4A1G
4QPM
4R8Q
5DMZ
6F7B
4WY4
7BV4
7BV6
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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