STX17 and MIS18A

Data Source:
BioGRID (two hybrid)

		STX17	MIS18A
Description		syntaxin 17	MIS18 kinetochore protein A
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Mitochondrion Lysosomal Membrane Autophagosome Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Endomembrane System ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane COPII-coated ER To Golgi Transport Vesicle Smooth Endoplasmic Reticulum Membrane HOPS Complex SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding Protein Phosphatase Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion Golgi Organization Autophagosome Membrane Docking Protein Localization To Phagophore Assembly Site Vesicle Docking Endoplasmic Reticulum-Golgi Intermediate Compartment Organization Autophagosome Maturation	Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Regulation Of DNA Methylation Cell Division
Pathways		COPII-mediated vesicle transport	Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS		Alopecia areata ( 20596022) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
Interacting Genes		23 interacting genes: ATG14 AURKA BUB1 CDH1 CTNNA1 DLC1 EGFR KRAS MAP2K4 MIS18A MLH1 MLH3 MSH2 NRAS ODC1 PTPN12 PTPN2 RB1 SMAD4 SNAP29 SRC STK11 TLR2	30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CCDC115 CNGA3 DMAP1 FNDC11 GCSH GLYCTK HJURP IFT20 MAFIP MBIP NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA ZNF471 ZNF655
Entrez ID		55014	54069
HPRD ID		05013	10749
Ensembl ID		ENSG00000136874	ENSG00000159055
Uniprot IDs		P56962	Q9NYP9
PDB IDs		4WY4 7BV4 7BV6
Enriched GO Terms of Interacting Partners?
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