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BUB1 and CTSV
Data Source:
BioGRID
(two hybrid)
BUB1
CTSV
Description
BUB1 mitotic checkpoint serine/threonine kinase
cathepsin V
Image
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Condensed Nuclear Chromosome Kinetochore
Condensed Nuclear Chromosome Outer Kinetochore
Nucleoplasm
Cytosol
Membrane
Intracellular Membrane-bounded Organelle
Extracellular Region
Extracellular Space
Lysosome
Lysosomal Lumen
Molecular Function
Protein Kinase Activity
Protein Binding
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Cysteine-type Endopeptidase Activity
Protein Binding
Cysteine-type Peptidase Activity
Biological Process
Protein Phosphorylation
Apoptotic Process
Regulation Of Sister Chromatid Cohesion
Mitotic Cell Cycle Checkpoint
Mitotic Spindle Assembly Checkpoint
Cell Population Proliferation
Viral Process
Cell Division
Meiotic Sister Chromatid Cohesion, Centromeric
Regulation Of Chromosome Segregation
Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Extracellular Matrix Disassembly
Regulation Of Keratinocyte Differentiation
Proteolysis Involved In Cellular Protein Catabolic Process
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Endosomal/Vacuolar pathway
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Trafficking and processing of endosomal TLR
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentation
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Drugs
3-amino-5-phenylpentane
4-Methylpiperazin-1-Yl Carbonyl Group
Diseases
GWAS
Interacting Genes
63 interacting genes:
AKT1
ALDOB
ANP32B
AOPEP
AP1B1
AP2B1
AP3B1
AP4B1
APC
ARIH2
BAAT
BUB3
CCDC180
CDC14B
CDC20
CDK1
CDK8
CORO2A
CRK
CTSV
CYLC2
DVL1
EIF4EBP1
FANCC
FBP1
FBP2
FBXO7
FRAT2
GALNT12
HDAC1
HEMGN
HRAS
HSD17B3
IGFBP3
KNL1
LEF1
MAP2K1
MAPK3
MSANTD3
NANS
PLK1
PPP2CB
PPP3R2
RAE1
RASA1
RDH12
SEC61B
SFRP2
SFRP4
SHC1
SMAD1
STX17
SVIL
TBC1D2
TDRD7
TGFB1
TMEFF1
TMOD1
TRMO
TSTD2
XPA
ZNF189
ZNF510
13 interacting genes:
APC
BMPR1A
BRAF
BUB1
CDKN2A
CTNNA1
DCC
DLC1
MLH1
MLH3
PDGFRL
RB1
SRC
Entrez ID
699
1515
HPRD ID
03907
04495
Ensembl ID
ENSG00000169679
ENSG00000136943
Uniprot IDs
B4DYG2
O43683
A0A024R141
B2R717
O60911
PDB IDs
2LAH
4A1G
4QPM
4R8Q
5DMZ
6F7B
1FH0
3H6S
3KFQ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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