STX17 and ATG14

Data Source:
BioGRID (pull down, affinity chromatography technology)

		STX17	ATG14
Description		syntaxin 17	autophagy related 14
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GO Annotations	Cellular Component	Autophagosome Membrane Mitochondrion Lysosomal Membrane Autophagosome Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Endomembrane System ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane COPII-coated ER To Golgi Transport Vesicle Smooth Endoplasmic Reticulum Membrane HOPS Complex SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane	Autophagosome Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Axoneme Phagophore Assembly Site Membrane Phosphatidylinositol 3-kinase Complex, Class III Mitochondria-associated Endoplasmic Reticulum Membrane Phagocytic Vesicle Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding Protein Phosphatase Binding	Protein Binding GTPase Binding
	Biological Process	Intracellular Protein Transport Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion Golgi Organization Autophagosome Membrane Docking Protein Localization To Phagophore Assembly Site Vesicle Docking Endoplasmic Reticulum-Golgi Intermediate Compartment Organization Autophagosome Maturation	Autophagosome Assembly Mitophagy Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Endosome To Lysosome Transport Cellular Response To Starvation Posttranscriptional Regulation Of Gene Expression Macroautophagy Autophagosome Membrane Docking Cellular Response To Glucose Starvation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Protein Complex Stability Regulation Of Triglyceride Metabolic Process Response To Mitochondrial Depolarisation
Pathways		COPII-mediated vesicle transport	Macroautophagy
Drugs
Diseases
GWAS		Alopecia areata ( 20596022) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)	Blood protein levels ( 28240269) Eosinophil percentage of white cells ( 32888494) Platelet distribution width ( 27863252) Statin-induced myopathy ( 31220337) Testicular germ cell tumor ( 28604728) White blood cell count ( 32888494)
Interacting Genes		23 interacting genes: ATG14 AURKA BUB1 CDH1 CTNNA1 DLC1 EGFR KRAS MAP2K4 MIS18A MLH1 MLH3 MSH2 NRAS ODC1 PTPN12 PTPN2 RB1 SMAD4 SNAP29 SRC STK11 TLR2	9 interacting genes: ATG13 EXOC1 FSD2 MIS18A RACK1 SNAPIN STX17 STYK1 ULK2
Entrez ID		55014	22863
HPRD ID		05013	13820
Ensembl ID		ENSG00000136874	ENSG00000126775
Uniprot IDs		P56962	Q6ZNE5
PDB IDs		4WY4 7BV4 7BV6	6HOL
Enriched GO Terms of Interacting Partners?
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