Wiki-Pi
About
Search
Browse
People
Updates
Search
ELOC and VHL
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, pull down)
HPRD
(in vitro, in vivo)
ELOC
VHL
Description
elongin C
von Hippel-Lindau tumor suppressor
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytosol
VCB Complex
Cul2-RING Ubiquitin Ligase Complex
Elongin Complex
Nucleus
Nucleoplasm
Mitochondrion
Endoplasmic Reticulum
Cytosol
Membrane
Molecular Function
Protein Binding
Protein-containing Complex Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Transcription Factor Binding
Enzyme Binding
Ubiquitin Ligase-substrate Adaptor Activity
Biological Process
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Ubiquitin-dependent Protein Catabolic Process
Viral Process
Protein Ubiquitination
Post-translational Protein Modification
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Negative Regulation Of Transcription By RNA Polymerase II
Cell Morphogenesis
Regulation Of Transcription, DNA-templated
Proteolysis
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Gene Expression
Protein Ubiquitination
Negative Regulation Of Apoptotic Process
Post-translational Protein Modification
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
Protein Stabilization
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Pathways
Formation of RNA Pol II elongation complex
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Vif-mediated degradation of APOBEC3G
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Neddylation
Regulation of expression of SLITs and ROBOs
Antigen processing: Ubiquitination & Proteasome degradation
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
SUMOylation of ubiquitinylation proteins
Neddylation
Replication of the SARS-CoV-1 genome
Replication of the SARS-CoV-2 genome
RHOBTB3 ATPase cycle
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
Renal cell carcinoma
von Hippel-Lindau syndrome
Congenital polycythemia; Familial erythrocytosis (ECYT)
GWAS
Interacting Genes
35 interacting genes:
ASB11
CBX5
CENPC
COMMD1
CPTP
CUL2
CUL3
CYP2J2
ECT2
EFNB3
ELOA2
ELOA3P
ELOB
EPOR
GHR
ID2
JTB
LRRC41
MCM7
MED8
METTL21C
MRAS
NOTCH4
PRAME
RCAN2
RNF7
SAT2
SERTAD1
SOCS1
SOCS3
SOCS6
USP33
VHL
WNT7B
ZYG11B
107 interacting genes:
ACTB
AKT1
APP
AR
AURKA
CAPN7
CAPZB
CASR
CBR1
CBX1
CBX3
CCNC
CCT3
CD44
CDC34
CDKN2A
CERKL
CHEK2
CLU
COL4A2
CSNK2A1
CUL2
CUL5
DGKI
DNAJA3
DVL2
E2F1
EEF1B2
EGLN1
ELOB
ELOC
EPAS1
EPOR
FKBP8
FLNA
FN1
GHET1
GPS1
H1-2
H2BC13
H4-16
HDAC1
HDAC2
HDAC3
HIF1A
HIF1AN
HIF3A
HNRNPA2B1
HNRNPD
HSF2BP
HSPA5
HSPA8
IKBKB
JADE1
KIF2C
KIF3A
KLF4
LANCL1
MAP1LC3B
MDFI
NCL
NR4A1
NR4A2
NR4A3
PDCD5
PIAS4
PLD1
PLD2
POLR2G
PPP5C
PRDX1
PRKCI
PRMT1
PRMT8
PSMC3
RB1CC1
RBPMS
RBPMS2
RBX1
RHOBTB3
RNF139
RPL21
RPL5
RPS15A
RWDD3
SARNP
SAT2
SKP2
SLC2A1
SLC3A2
SON
SP1
TPT1
TRIM28
UBE2D1
UBE2D2
UBE2I
UBE2S
USP20
USP33
USP9X
UXT
VAPB
VBP1
YY1AP1
ZNF197
ZNF512B
Entrez ID
6921
7428
HPRD ID
02875
01905
Ensembl ID
ENSG00000154582
ENSG00000134086
Uniprot IDs
A0A024R7Y5
Q15369
A0A024R2F2
A0A0S2Z4K1
P40337
PDB IDs
1LM8
1LQB
1VCB
2C9W
2IZV
2MA9
3DCG
3ZKJ
3ZNG
3ZRC
3ZRF
3ZTC
3ZTD
3ZUN
4AJY
4AWJ
4B95
4B9K
4BKS
4BKT
4N9F
4W9C
4W9D
4W9E
4W9F
4W9G
4W9H
4W9I
4W9J
4W9K
4W9L
4WQO
5BO4
5LLI
5N4W
5NVV
5NVW
5NVX
5NVY
5NVZ
5NW0
5NW1
5NW2
5T35
6BVB
6C5X
6FMI
6FMJ
6FMK
6GFX
6GFY
6GFZ
6GMN
6GMQ
6GMR
6GMX
6HAX
6HAY
6HR2
6I4X
6I5J
6I5N
6I7R
6P59
6R7F
6R7H
6R7N
6SIS
6V9H
6ZHC
1LM8
1LQB
1VCB
3ZRC
3ZRF
3ZTC
3ZTD
3ZUN
4AJY
4AWJ
4B95
4B9K
4BKS
4BKT
4W9C
4W9D
4W9E
4W9F
4W9G
4W9H
4W9I
4W9J
4W9K
4W9L
4WQO
5LLI
5N4W
5NVV
5NVW
5NVX
5NVY
5NVZ
5NW0
5NW1
5NW2
5T35
6BVB
6FMI
6FMJ
6FMK
6GFX
6GFY
6GFZ
6GMN
6GMQ
6GMR
6GMX
6HAX
6HAY
6HR2
6I7Q
6I7R
6R6H
6R7F
6SIS
6ZHC
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?