Description |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
MYC proto-oncogene, bHLH transcription factor |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Adult body size ( 32376654)
- Apolipoprotein B levels ( 32203549)
- Coronary artery disease ( 32469254 24262325 30104761 33020668)
- Coronary artery disease or ischemic stroke ( 24262325)
- Coronary artery disease or large artery stroke ( 24262325)
- Disorders of lipid metabolism ( 30166351)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Inflammatory skin disease ( 25574825)
- Ischemic stroke ( 29531354)
- LDL cholesterol ( 21347282)
- LDL cholesterol levels ( 32203549 30698716)
- LDL cholesterol levels in current drinkers ( 30698716)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Low density lipoprotein cholesterol levels ( 31969989)
- Medication use (HMG CoA reductase inhibitors) ( 31015401)
- Multiple sclerosis ( 31604244)
- Response to statins (LDL cholesterol change) ( 31969989)
- Stroke ( 29531354)
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Interacting Genes |
80 interacting genes:
ACTB
ACTL6A
AHR
AR
ARID1A
ARID1B
ARID2
BRCA1
BRWD1
CARM1
CBX5
CCNE1
CDK19
CDK8
CDKN2A
CDX2
CEBPA
CEBPB
CHD4
CHFR
CHMP5
CIITA
CREB1
CTNNB1
E2F6
ESR1
ETS2
FANCA
GATA1
GMNN
H2AX
H2BC21
H3-3A
H3C1
H3C14
H4C6
HSF1
HSF4
HSPB1
IKZF1
KLF1
MBD3
MDM2
MED17
MED6
MPHOSPH6
MRTFA
MYC
MYOCD
NR3C1
NR4A2
PABPN1
PALS2
PAX6
PBRM1
PHB
PTEN
RAP1A
RASSF1
RB1
RBL1
RBL2
RELB
RFXAP
SIN3A
SIN3B
SMARCB1
SMARCC1
SMARCE1
SOX4
SS18
SS18L1
STAT2
STAT3
STK11
SUMO2
TAF15
TMF1
TP53
ZMYND11
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178 interacting genes:
ACTL6A
AKT1
APP
ARAF
ARNT
ATAD2
AURKA
AXIN1
BCL2
BIN1
BRCA1
BRD3
BTRC
CALM1
CBLC
CCAR2
CCNE1
CCNT1
CDC6
CDC73
CDCA7L
CDK1
CDK4
CDK6
CDK8
CDK9
CDKN1B
CDKN2A
CDKN2B
CDKN2C
CEBPA
CEBPB
CEP57
CIP2A
CREBBP
CSNK2A1
CSNK2A2
DACH1
DNMT3A
EFNB1
ELF3
EP300
EP400
EPHA2
ERBB2
FBXO8
FBXW7
FBXW8
FGFR4
FZR1
GCN1
GLIS1
GLIS2
GPX2
GRM1
GSK3A
GSK3B
GTF2F1
GTF2F2
GTF2I
HGF
HIF1A
HSP90AA1
ING4
KAT2A
KAT2B
KAT5
KDELR2
KDM1A
KIDINS220
LATS2
LDOC1
MAP2K1
MAP2K5
MAPK1
MAPK14
MAPK3
MAPK7
MAPK8
MAX
MDM2
MED1
MED16
MEN1
MET
MLH1
MOK
MSH2
MXD1
MXI1
MYCBP
MYCBP2
NDRG1
NEK11
NF2
NFIC
NFYB
NFYC
NMI
NONO
NOTCH3
NSD3
NUCB1
PAK2
PARP10
PDGFRA
PFDN5
PIK3CA
PLAU
PLK1
PML
PPP2CA
PRDX1
PSMC3
PTEN
RAF1
RASSF1
RB1
RBL1
RELA
RIOX2
RUVBL1
RUVBL2
SAP130
SENP2
SF3B1
SKP1
SKP2
SMAD2
SMAD3
SMARCA2
SMARCA4
SMARCB1
SMARCC1
SNIP1
SNRNP70
SOX3
SOX4
SP1
SPAG9
STK11
SUPT3H
TADA2A
TAF12
TAF1B
TAF9
TBP
TEAD2
TERT
TFAP2A
TFAP2B
TIAM1
TONSL
TP53
TP73
TRIM55
TRIM6
TRIM63
TRRAP
TSC1
TUBA1A
TUBA1B
TUBA3C
TUBA4A
TUBA8
UBB
USP2
USP22
USP36
USP37
USP7
VDR
WT1
YAF2
YBX1
YY1
ZBTB17
ZNF281
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Entrez ID |
6597 |
4609 |
HPRD ID |
04459 |
01818 |
Ensembl ID |
ENSG00000127616
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ENSG00000136997
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Uniprot IDs |
A7E2E1
B3KNW7
P51532
Q9HBD4
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P01106
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PDB IDs |
2GRC
2H60
3UVD
5DKD
5EA1
6BGH
6HR2
6LTH
6LTJ
6SY2
6ZS2
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1A93
1EE4
1MV0
1NKP
2A93
2OR9
4Y7R
5I4Z
5I50
6C4U
6E16
6E24
6G6J
6G6K
6G6L
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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