Description |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
serine/threonine kinase 11 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Adult body size ( 32376654)
- Apolipoprotein B levels ( 32203549)
- Coronary artery disease ( 32469254 24262325 30104761 33020668)
- Coronary artery disease or ischemic stroke ( 24262325)
- Coronary artery disease or large artery stroke ( 24262325)
- Disorders of lipid metabolism ( 30166351)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Inflammatory skin disease ( 25574825)
- Ischemic stroke ( 29531354)
- LDL cholesterol ( 21347282)
- LDL cholesterol levels ( 32203549 30698716)
- LDL cholesterol levels in current drinkers ( 30698716)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Low density lipoprotein cholesterol levels ( 31969989)
- Medication use (HMG CoA reductase inhibitors) ( 31015401)
- Multiple sclerosis ( 31604244)
- Response to statins (LDL cholesterol change) ( 31969989)
- Stroke ( 29531354)
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- Asthma (childhood onset) ( 31036433)
- Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
- Crohn's disease ( 28067908)
- Inflammatory bowel disease ( 28067908)
- Lymphocyte counts ( 32888494 27863252)
- Lymphocyte percentage of white cells ( 32888494)
- Monocyte count ( 32888494)
- Neutrophil percentage of white cells ( 32888494)
- PR interval ( 32439900)
- Psychosis in Alzheimer's disease ( 22005930)
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Interacting Genes |
80 interacting genes:
ACTB
ACTL6A
AHR
AR
ARID1A
ARID1B
ARID2
BRCA1
BRWD1
CARM1
CBX5
CCNE1
CDK19
CDK8
CDKN2A
CDX2
CEBPA
CEBPB
CHD4
CHFR
CHMP5
CIITA
CREB1
CTNNB1
E2F6
ESR1
ETS2
FANCA
GATA1
GMNN
H2AX
H2BC21
H3-3A
H3C1
H3C14
H4C6
HSF1
HSF4
HSPB1
IKZF1
KLF1
MBD3
MDM2
MED17
MED6
MPHOSPH6
MRTFA
MYC
MYOCD
NR3C1
NR4A2
PABPN1
PALS2
PAX6
PBRM1
PHB
PTEN
RAP1A
RASSF1
RB1
RBL1
RBL2
RELB
RFXAP
SIN3A
SIN3B
SMARCB1
SMARCC1
SMARCE1
SOX4
SS18
SS18L1
STAT2
STAT3
STK11
SUMO2
TAF15
TMF1
TP53
ZMYND11
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134 interacting genes:
ABCB5
ADIPOR1
AKT1
ALDOB
ANP32B
APP
ARAF
ARG2
ARNT
ATM
AURKA
BCAS3
BECN1
BRAF
CAB39
CALM2
CBLC
CCDC180
CCND2
CCNE1
CD44
CDC14B
CDC37
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
CFL2
CRY2
CTSB
CYLC2
CYP17A1
D2HGDH
DACH1
EEF1A2
EPHA2
ERBB2
ERLEC1
ETV4
FAIM2
FBP1
FBP2
FGFR4
FZR1
GLIS2
GNPDA1
GRM1
HERC2
HGF
HIF1A
HRAS
IGFBP3
KAT2A
KDELR2
KLK7
LATS2
LEF1
LYPD3
MAP2K1
MAP2K3
MAP2K5
MAP2K6
MAP3K5
MAPK14
MAPK3
MAPRE1
MARK1
MARK2
MARK4
MDM2
MET
MOB4
MOCS2
MT-ND2
MYC
NANS
NAT2
NF2
PARD3
PDGFRA
PDXP
PHF23
PIK3CA
PLD3
PPP2CB
PRKAA1
PRKAA2
PRKACA
PRSS50
PTEN
RASA1
RASSF1
RHOBTB2
RPS6KA3
RPS6KA5
RPS6KB1
S100A14
SEPTIN9
SERPINB5
SIK1
SIRT1
SMAD1
SMARCA4
SNRK
SOX4
SPDEF
ST14
STK11IP
STK24
STRADA
STRADB
STX17
TBC1D23
TDRD7
TEAD2
TERT
THOP1
THRSP
TNFRSF1A
TNIP2
TP53
TRIM25
TRMO
TSG101
TUBA1A
TUBB4A
UBE2D2
VPS72
WT1
XPA
YWHAG
ZNF189
ZNF510
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Entrez ID |
6597 |
6794 |
HPRD ID |
04459 |
03740 |
Ensembl ID |
ENSG00000127616
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ENSG00000118046
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Uniprot IDs |
A7E2E1
B3KNW7
P51532
Q9HBD4
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A0A0S2Z4D1
Q15831
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PDB IDs |
2GRC
2H60
3UVD
5DKD
5EA1
6BGH
6HR2
6LTH
6LTJ
6SY2
6ZS2
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2WTK
4ZDR
5WXN
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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