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BCL2L2 and MGST2
Data Source:
BioGRID
(two hybrid)
BCL2L2
MGST2
Description
BCL2 like 2
microsomal glutathione S-transferase 2
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrial Outer Membrane
Bcl-2 Family Protein Complex
Nuclear Envelope
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Disordered Domain Specific Binding
Glutathione Transferase Activity
Leukotriene-C4 Synthase Activity
Glutathione Peroxidase Activity
Protein Binding
Enzyme Activator Activity
Identical Protein Binding
Glutathione Binding
Biological Process
Spermatogenesis
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Negative Regulation Of Apoptotic Process
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Lipid Metabolic Process
Glutathione Biosynthetic Process
Xenobiotic Metabolic Process
Response To Organonitrogen Compound
Leukotriene Biosynthetic Process
Response To Lipopolysaccharide
Membrane Lipid Catabolic Process
Positive Regulation Of Inflammatory Response
Regulation Of Catalytic Activity
Cellular Oxidant Detoxification
Glutathione Derivative Biosynthetic Process
Pathways
Glutathione conjugation
Aflatoxin activation and detoxification
Drugs
Navitoclax
Glutathione
Diseases
GWAS
Height (
28552196
)
Metabolite levels (
23823483
)
Interacting Genes
53 interacting genes:
ANKS6
APOC1
APOC2
APOC4
ATP5PF
BAD
BAK1
BAX
BBC3
BCL2L11
BHLHA9
BID
BIK
BMF
BNIP3
BNIP5
C10orf67
CD79A
CHODL
CIDEB
CISD2
CLDN7
ERVFRD-1
FATE1
G0S2
GORAB
GPR151
GPX8
HRK
KASH5
KCNJ6
LMNA
LRRIQ1
MGST2
MUC1
PANX1
PPP1CA
PSCA
RHBDD2
S100B
SAR1A
SGPL1
SLC35C2
SLC35E3
SLC39A2
SLC39A6
STOM
SUSD3
TCF4
TEX11
TMEM139
TMX1
TP53
23 interacting genes:
ASIC1
BCL2L10
BCL2L2
C3orf52
CCL3L3
CLEC14A
CREB3
CREB3L1
CTXN3
DNAJC30
GIMAP5
GJA8
GPX8
HDHD2
PLN
PNKP
SEC22A
SEC22B
SGCB
STX8
TMEM167B
TMEM207
VAMP3
Entrez ID
599
4258
HPRD ID
03569
03436
Ensembl ID
ENSG00000129473
ENSG00000085871
Uniprot IDs
Q92843
Q99735
PDB IDs
1MK3
1O0L
1ZY3
2Y6W
4CIM
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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