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MGST2 and SGCB
Data Source:
BioGRID
(two hybrid)
MGST2
SGCB
Description
microsomal glutathione S-transferase 2
sarcoglycan beta
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nuclear Envelope
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Cytoplasm
Cytoskeleton
Integral Component Of Plasma Membrane
Dystrophin-associated Glycoprotein Complex
Sarcoglycan Complex
Sarcolemma
Molecular Function
Glutathione Transferase Activity
Leukotriene-C4 Synthase Activity
Glutathione Peroxidase Activity
Protein Binding
Enzyme Activator Activity
Identical Protein Binding
Glutathione Binding
Protein Binding
Biological Process
Lipid Metabolic Process
Glutathione Biosynthetic Process
Xenobiotic Metabolic Process
Response To Organonitrogen Compound
Leukotriene Biosynthetic Process
Response To Lipopolysaccharide
Membrane Lipid Catabolic Process
Positive Regulation Of Inflammatory Response
Regulation Of Catalytic Activity
Cellular Oxidant Detoxification
Glutathione Derivative Biosynthetic Process
Muscle Organ Development
Muscle Fiber Development
Cardiac Muscle Cell Development
Vascular Associated Smooth Muscle Cell Development
Pathways
Glutathione conjugation
Aflatoxin activation and detoxification
Drugs
Glutathione
Diseases
Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F
Limb-girdle muscular dystrophy (LGMD)
GWAS
Metabolite levels (
23823483
)
Interacting Genes
23 interacting genes:
ASIC1
BCL2L10
BCL2L2
C3orf52
CCL3L3
CLEC14A
CREB3
CREB3L1
CTXN3
DNAJC30
GIMAP5
GJA8
GPX8
HDHD2
PLN
PNKP
SEC22A
SEC22B
SGCB
STX8
TMEM167B
TMEM207
VAMP3
22 interacting genes:
ADAM33
ADRA1A
APOL3
BRICD5
CLEC7A
CMTM5
EHHADH
HTR2C
LTB4R2
MAL
MGST2
NINJ1
PTTG1IP
SGCA
SGCD
SGCG
SGCZ
SLC52A1
SMIM3
TMEM11
TNF
TRIM63
Entrez ID
4258
6443
HPRD ID
03436
02942
Ensembl ID
ENSG00000085871
ENSG00000163069
Uniprot IDs
Q99735
Q16585
Q5U0N0
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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