MGST2 and SEC22A

Data Source:
BioGRID (two hybrid)

		MGST2	SEC22A
Description		microsomal glutathione S-transferase 2	SEC22 homolog A, vesicle trafficking protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Identical Protein Binding Glutathione Binding	Transporter Activity Protein Binding
	Biological Process	Lipid Metabolic Process Glutathione Biosynthetic Process Xenobiotic Metabolic Process Response To Organonitrogen Compound Leukotriene Biosynthetic Process Response To Lipopolysaccharide Membrane Lipid Catabolic Process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport
Pathways		Glutathione conjugation Aflatoxin activation and detoxification	COPII-mediated vesicle transport
Drugs		Glutathione
Diseases
GWAS		Metabolite levels ( 23823483)	Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		23 interacting genes: ASIC1 BCL2L10 BCL2L2 C3orf52 CCL3L3 CLEC14A CREB3 CREB3L1 CTXN3 DNAJC30 GIMAP5 GJA8 GPX8 HDHD2 PLN PNKP SEC22A SEC22B SGCB STX8 TMEM167B TMEM207 VAMP3	106 interacting genes: ADGRG3 AQP6 ASGR2 ATP6AP2 BIK BNIP3 C10orf67 C16orf54 C16orf92 CALN1 CD207 CD300A CD7 CD74 CISD2 CLEC10A CLEC12B CLEC2D CLEC7A CREB3L1 CYB561 CYBRD1 DDIT4L DIABLO DTX2 EDA ELOVL4 ERLIN1 ERVFRD-1 FAM174A FAM209A FATE1 FUT3 GAD2 GGT6 GJB5 GJB6 GPR37L1 GRAMD2B HAVCR2 HCST HSD17B11 ICAM3 KCNJ2 LDLRAD1 LHFPL5 LMNA LPAR6 LRRC25 LSMEM2 MCOLN1 MFF MGST2 MINAR1 MS4A14 MS4A3 MS4A4A MSR1 OPRM1 PACC1 PEX12 PHB PTGES RASGRP4 RETREG3 RILPL1 RNASEK RNF144A RNF19B RNF5 SAR1A SCN3B SDHAF2 SFTPC SLC14A2 SLC30A2 SLC35C2 SLC39A2 SMIM3 SPAG4 STMN4 STOML3 STX1A STX2 STX4 SUSD3 SYNE4 TFR2 TLCD4 TMED9 TMEM106C TMEM159 TMEM174 TMEM237 TMEM45B TMEM52B TMEM71 TMEM79 TMIE TMPRSS2 TNFSF14 TP53INP1 TRAT1 TRIM59 TYRP1 ZFYVE27
Entrez ID		4258	26984
HPRD ID		03436	15313
Ensembl ID		ENSG00000085871	ENSG00000121542
Uniprot IDs		Q99735	Q96IW7
PDB IDs
Enriched GO Terms of Interacting Partners?
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