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RAB3A and CHM
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro, two hybrid)
RAB3A
CHM
Description
RAB3A, member RAS oncogene family
CHM Rab escort protein
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Acrosomal Vesicle
Lysosome
Endosome
Cytosol
Plasma Membrane
Synaptic Vesicle
Axon
Secretory Granule Membrane
Protein-containing Complex
Terminal Bouton
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone
Clathrin-sculpted Acetylcholine Transport Vesicle Membrane
Clathrin-sculpted Glutamate Transport Vesicle Membrane
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Clathrin-sculpted Monoamine Transport Vesicle Membrane
Anchored Component Of Synaptic Vesicle Membrane
Extracellular Vesicle
Nucleus
Cytoplasm
Cytosol
Rab-protein Geranylgeranyltransferase Complex
Molecular Function
ATPase Activator Activity
GTPase Activity
Protein Binding
GTP Binding
Protein C-terminus Binding
GTP-dependent Protein Binding
Myosin V Binding
GDP-dissociation Inhibitor Binding
ATPase Binding
Rab Geranylgeranyltransferase Activity
GDP-dissociation Inhibitor Activity
GTPase Activator Activity
Protein Binding
Small GTPase Binding
Biological Process
Plasma Membrane Repair
Respiratory System Process
Exocytosis
Vesicle Docking Involved In Exocytosis
Mitochondrion Organization
Neurotransmitter Secretion
Neuromuscular Synaptic Transmission
Axonogenesis
Protein Secretion
Post-embryonic Development
Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Regulation Of Dopamine Secretion
Synaptic Vesicle Exocytosis
Synaptic Vesicle Maturation
Regulation Of Exocytosis
Lung Development
Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Lysosome Localization
Positive Regulation Of ATPase Activity
Synaptic Vesicle Recycling
Neutrophil Degranulation
Post-translational Protein Modification
Constitutive Secretory Pathway
Regulated Exocytosis
Positive Regulation Of Exocytosis
Regulation Of Short-term Neuronal Synaptic Plasticity
Synaptic Vesicle Transport
Maintenance Of Presynaptic Active Zone Structure
Sensory Perception Of Touch
Response To Electrical Stimulus
Acrosomal Vesicle Exocytosis
Evoked Neurotransmitter Secretion
Protein Localization To Plasma Membrane
Synaptic Vesicle Clustering
Positive Regulation Of Regulated Secretory Pathway
Regulation Of Plasma Membrane Repair
Regulation Of Synaptic Vesicle Exocytosis
Protein Targeting To Membrane
Small GTPase Mediated Signal Transduction
Visual Perception
Vesicle-mediated Transport
Protein Phosphopantetheinylation
Protein Geranylgeranylation
Regulation Of Apoptotic Process
Positive Regulation Of GTPase Activity
Post-translational Protein Modification
Pathways
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Neutrophil degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
GABA synthesis, release, reuptake and degradation
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
Choroideremia (CHM); Tapetochoroidal dystrophy
GWAS
Emphysema annual change measurement in smokers (percent low attenuation area) (
31324189
)
Metabolite levels (
23823483
)
Pit-and-Fissure caries (
24556642
)
Smooth-surface caries (
24556642
)
Interacting Genes
29 interacting genes:
A2M
ADRB2
AP1M2
APP
CASK
CHM
CHML
CHRM4
DMXL2
ECSIT
EGFR
KRTAP10-8
MAST1
MYO5A
PSEN1
RAB3IL1
RAB3IP
RABAC1
RABGGTB
RABIF
RIMS1
RIMS2
RNF32
RPH3A
RPH3AL
SGSM2
SYTL4
SYTL5
VRTN
11 interacting genes:
RAB14
RAB18
RAB1B
RAB32
RAB3A
RAB3B
RAB3D
RAB4A
RAB5B
RAB6A
RAB7A
Entrez ID
5864
1121
HPRD ID
01535
02312
Ensembl ID
ENSG00000105649
ENSG00000188419
Uniprot IDs
A0A024R7I7
P20336
A8K545
B4DRL9
P24386
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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