RAB3A and RAB3IP

Data Source:
HPRD (in vitro, two hybrid)

		RAB3A	RAB3IP
Description		RAB3A, member RAS oncogene family	RAB3A interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Lysosome Endosome Cytosol Plasma Membrane Synaptic Vesicle Axon Secretory Granule Membrane Protein-containing Complex Terminal Bouton Perinuclear Region Of Cytoplasm Presynaptic Active Zone Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Clathrin-sculpted Glutamate Transport Vesicle Membrane Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane Extracellular Vesicle	Nucleus Cytosol Cytoskeleton Lamellipodium Golgi To Plasma Membrane Transport Vesicle
	Molecular Function	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding Protein C-terminus Binding GTP-dependent Protein Binding Myosin V Binding GDP-dissociation Inhibitor Binding ATPase Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Plasma Membrane Repair Respiratory System Process Exocytosis Vesicle Docking Involved In Exocytosis Mitochondrion Organization Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axonogenesis Protein Secretion Post-embryonic Development Regulation Of Synaptic Vesicle Priming Glutamate Secretion Regulation Of Dopamine Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Regulation Of Exocytosis Lung Development Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Positive Regulation Of ATPase Activity Synaptic Vesicle Recycling Neutrophil Degranulation Post-translational Protein Modification Constitutive Secretory Pathway Regulated Exocytosis Positive Regulation Of Exocytosis Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Transport Maintenance Of Presynaptic Active Zone Structure Sensory Perception Of Touch Response To Electrical Stimulus Acrosomal Vesicle Exocytosis Evoked Neurotransmitter Secretion Protein Localization To Plasma Membrane Synaptic Vesicle Clustering Positive Regulation Of Regulated Secretory Pathway Regulation Of Plasma Membrane Repair Regulation Of Synaptic Vesicle Exocytosis	Protein Targeting To Membrane Exocytosis Regulation Of Catalytic Activity Ciliary Basal Body-plasma Membrane Docking
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs GABA synthesis, release, reuptake and degradation	Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)	Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		29 interacting genes: A2M ADRB2 AP1M2 APP CASK CHM CHML CHRM4 DMXL2 ECSIT EGFR KRTAP10-8 MAST1 MYO5A PSEN1 RAB3IL1 RAB3IP RABAC1 RABGGTB RABIF RIMS1 RIMS2 RNF32 RPH3A RPH3AL SGSM2 SYTL4 SYTL5 VRTN	32 interacting genes: BANP CCDC196 CHCHD3 DNAJB13 FAM124A KRT40 MB21D2 MBD3 MVP NAA10 PEG10 PKN1 PLOD3 PPL PRKAB2 RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TBC1D21 TEPSIN TRAPPC6A TXNDC5 ZBTB16 ZNF410 ZNF76
Entrez ID		5864	117177
HPRD ID		01535	10565
Ensembl ID		ENSG00000105649	ENSG00000127328
Uniprot IDs		A0A024R7I7 P20336	Q96QF0
PDB IDs			4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P
Enriched GO Terms of Interacting Partners?
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