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CHM

Description CHM Rab escort protein
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Rab-protein Geranylgeranyltransferase Complex
Molecular Function
  • Rab Geranylgeranyltransferase Activity
  • GDP-dissociation Inhibitor Activity
  • GTPase Activator Activity
  • Protein Binding
  • Small GTPase Binding
Biological Process
  • Protein Targeting To Membrane
  • Small GTPase Mediated Signal Transduction
  • Visual Perception
  • Vesicle-mediated Transport
  • Protein Phosphopantetheinylation
  • Protein Geranylgeranylation
  • Regulation Of Apoptotic Process
  • Positive Regulation Of GTPase Activity
  • Post-translational Protein Modification
Pathways
  • TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
  • RAB geranylgeranylation
  • RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
  • Choroideremia (CHM); Tapetochoroidal dystrophy
GWAS
  • Metabolite levels ( 23823483)
  • Pit-and-Fissure caries ( 24556642)
  • Smooth-surface caries ( 24556642)
Interacting Genes 11 interacting genes: RAB14 RAB18 RAB1B RAB32 RAB3A RAB3B RAB3D RAB4A RAB5B RAB6A RAB7A
Entrez ID 1121
HPRD ID 02312
Ensembl ID ENSG00000188419
Uniprot IDs A8K545 B4DRL9 P24386
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025