PRPH2 and ROM1

Data Source:
HPRD (in vivo, in vitro)

		PRPH2	ROM1
Description		peripherin 2	retinal outer segment membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Integral Component Of Plasma Membrane Integral Component Of Membrane	Integral Component Of Plasma Membrane Photoreceptor Outer Segment Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding Protein Homodimerization Activity
	Biological Process	Cell Adhesion Visual Perception Photoreceptor Cell Outer Segment Organization Detection Of Light Stimulus Involved In Visual Perception Protein Homooligomerization Protein Heterooligomerization Retina Development In Camera-type Eye	Cell Adhesion Visual Perception Regulation Of Gene Expression Photoreceptor Cell Outer Segment Organization Detection Of Light Stimulus Involved In Visual Perception Protein Homooligomerization Protein Heterooligomerization Camera-type Eye Photoreceptor Cell Differentiation Retina Vasculature Development In Camera-type Eye Protein Localization To Photoreceptor Outer Segment
Pathways
Drugs
Diseases		Vitelliform macular dystrophy, including: Best disease / Juvenile vitelliform macular dystrophy (VMD2) ; Adult-onset vitelliform macular dystrophy (AVMD) Retinitis pigmentosa (RP) Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA)
GWAS		Pulse pressure ( 27841878)	Serum bilirubin levels in metabolic syndrome ( 30621171) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: CNGB1 GRAP2 PRPH ROM1	2 interacting genes: ORMDL3 PRPH2
Entrez ID		5961	6094
HPRD ID		01553	01616
Ensembl ID		ENSG00000112619	ENSG00000149489
Uniprot IDs		P23942	Q03395
PDB IDs
Enriched GO Terms of Interacting Partners?
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