VRTN and POLR3C

Data Source:
BioGRID (two hybrid)

		VRTN	POLR3C
Description		vertebrae development associated	RNA polymerase III subunit C
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin	Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	Transposase Activity Protein Binding Sequence-specific DNA Binding	Single-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	Transposition, DNA-mediated Regulation Of Transcription By RNA Polymerase II	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways			Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		FEV1 ( 30804560) Lung function (FVC) ( 30804560) Refractive error ( 32231278)
Interacting Genes		10 interacting genes: C9orf72 CTBP2 EIF4A3 FAM90A1 POLR3C RAB2B RAB3A RAB3B RAB3C RAB3D	39 interacting genes: ANKRD23 APP CAMK2B CEP44 CEP63 COIL DISC1 ENKD1 GOLGA2 GTF3C4 HAUS1 INCA1 KATNBL1 KIAA0408 KLHL2 KPNA1 KPNA3 KPNA5 KPNA6 KRT75 LZTS1 NCKIPSD PAX6 PICK1 PNMA5 POLR3G POLR3GL POU6F2 PRDM16 RBBP8NL ROCK1 ROPN1 SP100 TNR TRAF2 TRIM27 UBXN1 VAX1 VRTN
Entrez ID		55237	10623
HPRD ID		16593	17880
Ensembl ID		ENSG00000133980	ENSG00000186141
Uniprot IDs		Q9H8Y1	Q9BUI4
PDB IDs			2XUB 2XV4 5AFQ
Enriched GO Terms of Interacting Partners?
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