RHCG and TMEM60

Data Source:
BioGRID (two hybrid)

		RHCG	TMEM60
Description		Rh family C glycoprotein	transmembrane protein 60
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	Protein Binding Ammonium Transmembrane Transporter Activity Ankyrin Binding Identical Protein Binding	Protein Binding
	Biological Process	Cellular Ion Homeostasis Regulation Of PH Ammonium Transport Amine Transport Epithelial Cell Differentiation Homeostatic Process Transepithelial Ammonium Transport Ammonium Transmembrane Transport
Pathways		Rhesus glycoproteins mediate ammonium transport.
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)	Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199)
Interacting Genes		14 interacting genes: C1QL4 C4orf3 CXCL9 EFNA5 ERMP1 FXYD6 GPR25 IGFBP5 MS4A13 TMEM60 TMEM97 TRARG1 UPK1B YIPF6	89 interacting genes: AMIGO1 ANKS6 APOL2 AQP2 AQP6 ASGR2 BEST2 BIK BSND CD300A CD53 CD74 CLDN7 CNR2 CPLX4 CYB5R3 EBP EDA ERGIC3 EVI2B FAM209A FFAR2 FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPR42 GPX8 HERPUD2 HIBADH HSD17B13 IFNGR2 KCNK5 KIAA2013 LEUTX LHFPL5 LMNA LRRC3B LRRC59 MFF MGST3 MMD MMGT1 PAGE1 PGRMC2 PI16 REEP2 REEP4 RETREG3 RHCG RNASEK SCN3B SLC10A1 SLC10A6 SLC13A4 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC30A4 SLC35E3 SLC38A1 SLC39A2 SLC4A1 SLC7A8 SPAG4 SPNS3 SSMEM1 STOM STX1A SYT1 THAP4 TLCD4 TMCO5A TMED9 TMEM139 TMEM14B TMEM203 TMEM237 TMEM45B TMEM52B TMEM86B TMEM9 TMPPE TMPRSS2 TTYH1 VMA21
Entrez ID		51458	85025
HPRD ID		16102	12923
Ensembl ID		ENSG00000140519	ENSG00000135211
Uniprot IDs		Q9UBD6	Q9H2L4
PDB IDs		3HD6
Enriched GO Terms of Interacting Partners?
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