RHCG and GPR25

Data Source:
BioGRID (two hybrid)

		RHCG	GPR25
Description		Rh family C glycoprotein	G protein-coupled receptor 25
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Ammonium Transmembrane Transporter Activity Ankyrin Binding Identical Protein Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Cellular Ion Homeostasis Regulation Of PH Ammonium Transport Amine Transport Epithelial Cell Differentiation Homeostatic Process Transepithelial Ammonium Transport Ammonium Transmembrane Transport	G Protein-coupled Receptor Signaling Pathway
Pathways		Rhesus glycoproteins mediate ammonium transport.	G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)	Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: C1QL4 C4orf3 CXCL9 EFNA5 ERMP1 FXYD6 GPR25 IGFBP5 MS4A13 TMEM60 TMEM97 TRARG1 UPK1B YIPF6	32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB
Entrez ID		51458	2848
HPRD ID		16102	03707
Ensembl ID		ENSG00000140519	ENSG00000170128
Uniprot IDs		Q9UBD6	O00155
PDB IDs		3HD6
Enriched GO Terms of Interacting Partners?
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