TMEM60 and TTYH1

Data Source:
BioGRID (two hybrid)

		TMEM60	TTYH1
Description		transmembrane protein 60	tweety family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane Smooth Endoplasmic Reticulum Membrane Filopodium Membrane Filopodium Tip Chloride Channel Complex Synapse
	Molecular Function	Protein Binding	Intracellular Calcium Activated Chloride Channel Activity Chloride Channel Activity Iron Ion Transmembrane Transporter Activity Calcium Ion Binding Protein Binding Volume-sensitive Chloride Channel Activity
	Biological Process		Mitotic Cell Cycle Chloride Transport Iron Ion Transport Cell-substrate Adhesion Ion Transmembrane Transport Iron Ion Transmembrane Transport Filopodium Assembly Cell-cell Adhesion Chloride Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199)	Blood trace element (Se levels) ( 23720494) Idiopathic pulmonary fibrosis ( 29066090)
Interacting Genes		89 interacting genes: AMIGO1 ANKS6 APOL2 AQP2 AQP6 ASGR2 BEST2 BIK BSND CD300A CD53 CD74 CLDN7 CNR2 CPLX4 CYB5R3 EBP EDA ERGIC3 EVI2B FAM209A FFAR2 FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPR42 GPX8 HERPUD2 HIBADH HSD17B13 IFNGR2 KCNK5 KIAA2013 LEUTX LHFPL5 LMNA LRRC3B LRRC59 MFF MGST3 MMD MMGT1 PAGE1 PGRMC2 PI16 REEP2 REEP4 RETREG3 RHCG RNASEK SCN3B SLC10A1 SLC10A6 SLC13A4 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC30A4 SLC35E3 SLC38A1 SLC39A2 SLC4A1 SLC7A8 SPAG4 SPNS3 SSMEM1 STOM STX1A SYT1 THAP4 TLCD4 TMCO5A TMED9 TMEM139 TMEM14B TMEM203 TMEM237 TMEM45B TMEM52B TMEM86B TMEM9 TMPPE TMPRSS2 TTYH1 VMA21	5 interacting genes: CCR9 DRD2 GPR37 HTR6 TMEM60
Entrez ID		85025	57348
HPRD ID		12923	12043
Ensembl ID		ENSG00000135211	ENSG00000167614
Uniprot IDs		Q9H2L4	Q9H313
PDB IDs
Enriched GO Terms of Interacting Partners?
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