PLEKHO1 and LRP10

		PLEKHO1	LRP10
Description		pleckstrin homology domain containing O1	LDL receptor related protein 10
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane	Clathrin-coated Pit Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Low-density Lipoprotein Particle Receptor Activity Protein Binding
	Biological Process	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis	Lipid Metabolic Process Lipid Transport Endocytosis Inner Ear Development
Pathways			Retinoid metabolism and transport
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Neutrophil count ( 32888494)
Interacting Genes		32 interacting genes: ADAM33 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C4orf3 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB IFI35 LRP10 MMD NAPB PSMC5 RPS20 SMAD5 SMURF1 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1	23 interacting genes: C16orf92 CISD2 EBP FAM209A GGA3 GJB5 GOLM2 GORAB HTRA1 LMNA MFSD14B MGST3 MRPS18B NOTO PDCD1LG2 PLEKHO1 SLC10A1 SLC14A2 SMIM1 ST6GALNAC6 TMEM179B TMEM237 TMEM243
Entrez ID		51177	26020
HPRD ID		12217	14311
Ensembl ID		ENSG00000023902	ENSG00000197324
Uniprot IDs		Q53GL0 Q5T4P9	Q7Z4F1
PDB IDs		3AA1
Enriched GO Terms of Interacting Partners?
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