LRP10 and SLC14A2

Data Source:
BioGRID (two hybrid)

		LRP10	SLC14A2
Description		LDL receptor related protein 10	solute carrier family 14 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Clathrin-coated Pit Membrane Integral Component Of Membrane	Plasma Membrane Membrane Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Protein Binding	Protein Binding Urea Transmembrane Transporter Activity Cell Adhesion Molecule Binding
	Biological Process	Lipid Metabolic Process Lipid Transport Endocytosis Inner Ear Development	Urea Transport Transmembrane Transport Urea Transmembrane Transport
Pathways		Retinoid metabolism and transport	Transport of bile salts and organic acids, metal ions and amine compounds
Drugs
Diseases
GWAS		Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Neutrophil count ( 32888494)	Biochemical measures ( 19260141) Bladder cancer ( 24163127) Blood urea nitrogen levels ( 31152163 29403010) Cerebrospinal fluid clusterin levels ( 26545630) Cocaine dependence ( 31212010) FEV1 ( 30804560) Follicular lymphoma ( 25279986) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hematological and biochemical traits ( 20139978) Hemoglobin ( 32888494) Intake of total sugars ( 31005972) Lateral orbital frontal cortex volume ( 31530798) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Male-pattern baldness ( 27182965 28196072) Menarche (age at onset) ( 21102462) Metabolite levels ( 21909109 23823483) Nicotine withdrawal ( 29532581) Nicotine withdrawal symptom count ( 29532581) Pulse pressure ( 28135244 27841878) Red blood cell count ( 32888494) Refractive error ( 32231278) Renal function-related traits (BUN) ( 22797727) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969) Systolic blood pressure ( 27841878) Urate levels ( 31578528)
Interacting Genes		23 interacting genes: C16orf92 CISD2 EBP FAM209A GGA3 GJB5 GOLM2 GORAB HTRA1 LMNA MFSD14B MGST3 MRPS18B NOTO PDCD1LG2 PLEKHO1 SLC10A1 SLC14A2 SMIM1 ST6GALNAC6 TMEM179B TMEM237 TMEM243	12 interacting genes: C4orf3 CMTM7 EHHADH LAT LRP10 PLN PLP2 SEC22A TMEM97 TNF TRARG1 VAMP5
Entrez ID		26020	8170
HPRD ID		14311	03366
Ensembl ID		ENSG00000197324	ENSG00000132874
Uniprot IDs		Q7Z4F1	Q15849
PDB IDs
Enriched GO Terms of Interacting Partners?
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