PLEKHO1 and TRAM1L1

Data Source:
BioGRID (two hybrid)

		PLEKHO1	TRAM1L1
Description		pleckstrin homology domain containing O1	translocation associated membrane protein 1 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ruffle Membrane Muscle Cell Projection Membrane	Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Myoblast Fusion Regulation Of Cell Shape Myoblast Migration Lamellipodium Morphogenesis	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Bronchopulmonary dysplasia ( 23897914) Lateral ventricle volume in trauma-exposed individuals ( 29187748) Metabolite levels ( 23823483) Obesity (extreme) ( 19553259) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		32 interacting genes: ADAM33 AKT1 AKT2 BNIP2 BRICD5 C10orf88 C4orf3 CEP19 COL8A2 CSNK2A1 CYP4F2 DNAJB1 FLNB IFI35 LRP10 MMD NAPB PSMC5 RPS20 SMAD5 SMURF1 THSD7B TMEM218 TNF TRAF3IP3 TRAF6 TRAM1L1 TSPAN33 TSPO2 USP7 VAMP3 ZFPL1	29 interacting genes: ASGR2 BDKRB1 BSCL2 CD53 CD79A CD99L2 CLEC1A CLSTN3 CREB3 CREB3L1 CYBC1 ERGIC3 EVI2B FAM209A FKBP7 GPX8 HTR2B LMNA LRRC59 MFF MUC1 PLEKHF2 PLEKHO1 PLPP2 SAR1A TMED8 TMEM52B TMEM79 TMX2
Entrez ID		51177	133022
HPRD ID		12217	11643
Ensembl ID		ENSG00000023902	ENSG00000174599
Uniprot IDs		Q53GL0 Q5T4P9	Q8N609
PDB IDs		3AA1
Enriched GO Terms of Interacting Partners?
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