MYO15A and WHRN

Data Source:
HPRD (in vitro, in vivo)

		MYO15A	WHRN
Description		myosin XVA	whirlin
Image
GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton Myosin Complex Vesicle Stereocilium Extracellular Exosome Actin-based Cell Projection	Photoreceptor Inner Segment Stereocilia Ankle Link Stereocilia Ankle Link Complex Cytoplasm Actin Filament Plasma Membrane Growth Cone Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Ciliary Basal Body Neuronal Cell Body Synapse Periciliary Membrane Compartment USH2 Complex
	Molecular Function	Microfilament Motor Activity Calmodulin Binding ATP Binding Actin-dependent ATPase Activity Actin Filament Binding	Protein Binding Identical Protein Binding
	Biological Process	Actin Filament Organization Sensory Perception Of Sound Vesicle Transport Along Actin Filament	Retina Homeostasis Sensory Perception Of Sound Positive Regulation Of Gene Expression Cerebellar Purkinje Cell Layer Formation Establishment Of Protein Localization Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Sensory Perception Of Light Stimulus Auditory Receptor Cell Stereocilium Organization Inner Ear Receptor Cell Stereocilium Organization Paranodal Junction Maintenance
Pathways
Drugs
Diseases		Deafness, autosomal recessive	Usher syndrome (US) Deafness, autosomal recessive
GWAS		Change in neurofilament light levels ( 31295725) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Red blood cell count ( 32888494) Schizophrenia ( 25056061) Serum folate levels ( 29953918)
Interacting Genes		4 interacting genes: EPS8 FASLG USP13 WHRN	17 interacting genes: BEND7 BMI1 CASK COL17A1 EFHC1 GOLGA2 GPSM2 HEMGN KEAP1 LRP4 LRRC4C MYO15A MYO7A PXN RPS6KA1 SPC24 TPRN
Entrez ID		51168	25861
HPRD ID		04049	09718
Ensembl ID		ENSG00000091536	ENSG00000095397
Uniprot IDs		Q9UKN7	B9EGE6 Q9P202
PDB IDs		6KZ1	1UEZ 1UF1 1UFX 6KZ1
Enriched GO Terms of Interacting Partners?
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